Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping Review

Acute pancreatitis; Antibiotics; Duration of treatment

Detalhes bibliográficos
Autores: Badia, Josep M, Amador-Gil, Sara, Gonzalez-Sanchez, Carmen, Rubio-Perez, Ines, Manuel-Vazquez, Alba, Juvany, Montserrat, GUIRAO, XAVIER, Membrilla Fernández, Estela, Balibrea, José M.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:11351/13824
Acesso em linha:http://hdl.handle.net/11351/13824
Access Level:acceso abierto
Palavra-chave:Pancreatitis
Antibiòtics
Microbiologia
DISEASES::Digestive System Diseases::Pancreatic Diseases::Pancreatitis
CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents
CHEMICALS AND DRUGS::Biological Factors::Biomarkers
ENFERMEDADES::enfermedades del sistema digestivo::enfermedades pancreáticas::pancreatitis
COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos::antibacterianos
COMPUESTOS QUÍMICOS Y DROGAS::factores biológicos::biomarcadores
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oai_identifier_str oai:recercat.cat:11351/13824
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping Review
title Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping Review
spellingShingle Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping Review
Badia, Josep M
Pancreatitis
Antibiòtics
Microbiologia
DISEASES::Digestive System Diseases::Pancreatic Diseases::Pancreatitis
CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents
CHEMICALS AND DRUGS::Biological Factors::Biomarkers
ENFERMEDADES::enfermedades del sistema digestivo::enfermedades pancreáticas::pancreatitis
COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos::antibacterianos
COMPUESTOS QUÍMICOS Y DROGAS::factores biológicos::biomarcadores
title_short Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping Review
title_full Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping Review
title_fullStr Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping Review
title_full_unstemmed Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping Review
title_sort Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping Review
dc.creator.none.fl_str_mv Badia, Josep M
Amador-Gil, Sara
Gonzalez-Sanchez, Carmen
Rubio-Perez, Ines
Manuel-Vazquez, Alba
Juvany, Montserrat
GUIRAO, XAVIER
Membrilla Fernández, Estela
Balibrea, José M.
author Badia, Josep M
author_facet Badia, Josep M
Amador-Gil, Sara
Gonzalez-Sanchez, Carmen
Rubio-Perez, Ines
Manuel-Vazquez, Alba
Juvany, Montserrat
GUIRAO, XAVIER
Membrilla Fernández, Estela
Balibrea, José M.
author_role author
author2 Amador-Gil, Sara
Gonzalez-Sanchez, Carmen
Rubio-Perez, Ines
Manuel-Vazquez, Alba
Juvany, Montserrat
GUIRAO, XAVIER
Membrilla Fernández, Estela
Balibrea, José M.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv [Badia JM, Amador S] Department of Surgery, Hospital General de Granollers, School of Medicine, Universitat Internacional de Catalunya, Granollers, Spain. [González-Sánchez C] Department of Surgery, Hospital Universitario de Salamanca, Salamanca, Spain. [Rubio-Pérez I] Department of Surgery, Hospital Universitario La Paz, Madrid, Spain. [Manuel-Vázquez A] Department of Surgery, Hospital Universitario de Getafe, Getafe, Spain. [Juvany M, Membrilla E] Department of Surgery, Hospital del Mar, Barcelona, Spain. [Balibrea JM] Department of Surgery, Hospital Universitari Germans Trias, Badalona, Spain. [Guirao X] Department of Surgery, Hospital Universitari Parc Taulí, Sabadell, Spain
Hospital General de Granollers
dc.subject.none.fl_str_mv Pancreatitis
Antibiòtics
Microbiologia
DISEASES::Digestive System Diseases::Pancreatic Diseases::Pancreatitis
CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents
CHEMICALS AND DRUGS::Biological Factors::Biomarkers
ENFERMEDADES::enfermedades del sistema digestivo::enfermedades pancreáticas::pancreatitis
COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos::antibacterianos
COMPUESTOS QUÍMICOS Y DROGAS::factores biológicos::biomarcadores
topic Pancreatitis
Antibiòtics
Microbiologia
DISEASES::Digestive System Diseases::Pancreatic Diseases::Pancreatitis
CHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents
CHEMICALS AND DRUGS::Biological Factors::Biomarkers
ENFERMEDADES::enfermedades del sistema digestivo::enfermedades pancreáticas::pancreatitis
COMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos::antibacterianos
COMPUESTOS QUÍMICOS Y DROGAS::factores biológicos::biomarcadores
description Acute pancreatitis; Antibiotics; Duration of treatment
publishDate 2024
dc.date.none.fl_str_mv 2024
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/11351/13824
http://hdl.handle.net/11351/13824
url http://hdl.handle.net/11351/13824
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Antibiotics (Basel);13(9)
https://doi.org/10.3390/antibiotics13090894
dc.rights.none.fl_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Scientia
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869406841566396416
spelling Appropriate Use of Antibiotics in Acute Pancreatitis: A Scoping ReviewBadia, Josep MAmador-Gil, SaraGonzalez-Sanchez, CarmenRubio-Perez, InesManuel-Vazquez, AlbaJuvany, MontserratGUIRAO, XAVIERMembrilla Fernández, EstelaBalibrea, José M.PancreatitisAntibiòticsMicrobiologiaDISEASES::Digestive System Diseases::Pancreatic Diseases::PancreatitisCHEMICALS AND DRUGS::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial AgentsCHEMICALS AND DRUGS::Biological Factors::BiomarkersENFERMEDADES::enfermedades del sistema digestivo::enfermedades pancreáticas::pancreatitisCOMPUESTOS QUÍMICOS Y DROGAS::acciones y usos químicos::acciones farmacológicas::usos terapéuticos::antiinfecciosos::antibacterianosCOMPUESTOS QUÍMICOS Y DROGAS::factores biológicos::biomarcadoresAcute pancreatitis; Antibiotics; Duration of treatmentPancreatitis aguda; Antibióticos; Duración del tratamientoPancreatitis aguda; Antibiòtics; Durada del tractamentBackground: While selective use of antibiotics for infected pancreatic necrosis (IPN) in acute pancreatitis (AP) is recommended, studies indicate a high rate of inadequate treatment. Methods: A search of PubMed, Scopus, and Cochrane databases was conducted, focusing on primary research and meta-analyses. Data were categorized based on core concepts, and a narrative synthesis was performed. Results: The search identified a total of 1016 publications. After evaluating 203 full texts and additional sources from the grey literature, 80 studies were included in the review. The answers obtained were: (1) Preventive treatment does not decrease the incidence of IPN or mortality. Given the risks of bacterial resistance and fungal infections, antibiotics should be reserved for highly suspected or confirmed IPN; (2) The diagnosis of IPN does not always require microbiological samples, as clinical suspicion or computed tomography signs can suffice. Early diagnosis and treatment may be improved by using biomarkers such as procalcitonin and novel microbiological methods; (3) When indicated, early initiation of antibiotics is a key determinant in reducing mortality associated with IPN; (4) Antibiotics with good penetration into pancreatic tissue covering Gram-negative and Gram-positive bacteria should be used. Routine antifungal therapy is not recommended; (5) The step-up approach, including antibiotics, is the standard for IPN management; (6) Antibiotic duration should be kept to a minimum and should be based on the quality of source control and patient condition. Conclusions: Early antibiotic therapy is essential for the treatment of IPN, but prophylactic antibiotics are not recommended in AP. High-quality randomized controlled trials are required to better understand the role of antibiotics and antifungals in AP management.MDPI[Badia JM, Amador S] Department of Surgery, Hospital General de Granollers, School of Medicine, Universitat Internacional de Catalunya, Granollers, Spain. [González-Sánchez C] Department of Surgery, Hospital Universitario de Salamanca, Salamanca, Spain. [Rubio-Pérez I] Department of Surgery, Hospital Universitario La Paz, Madrid, Spain. [Manuel-Vázquez A] Department of Surgery, Hospital Universitario de Getafe, Getafe, Spain. [Juvany M, Membrilla E] Department of Surgery, Hospital del Mar, Barcelona, Spain. [Balibrea JM] Department of Surgery, Hospital Universitari Germans Trias, Badalona, Spain. [Guirao X] Department of Surgery, Hospital Universitari Parc Taulí, Sabadell, SpainHospital General de Granollers202520252024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/11351/13824http://hdl.handle.net/11351/13824Scientiareponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésAntibiotics (Basel);13(9)https://doi.org/10.3390/antibiotics13090894Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:recercat.cat:11351/138242026-05-29T05:05:01Z
score 15,198674

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