Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancer

MicroRNAs (miRNAs) are small molecules of single strand non-coding RNAs, which are able to regulate gene expression. miRNAs have been involved in multiple cellular processes, such as proliferation, apoptosis and differentiation, thus alterations in miRNA expression have been shown to be directly lin...

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Detalles Bibliográficos
Autores: Valladares Ayerbes, Manuel, Haz Conde, María del Mar, Blanco Calvo, Moisés, Antón Aparicio, Luis Miguel, Figueroa Conde-Valvís, Angélica, Calvo Martínez, Lourdes
Tipo de recurso: artículo
Fecha de publicación:2012
País:España
Institución:Servizo Galego de Saúde (SERGAS)
Repositorio:RUNA. Repositorio da Consellería de Sanidade e Sergas
OAI Identifier:oai:runa.sergas.gal:20.500.11940/7455
Acceso en línea:http://hdl.handle.net/20.500.11940/7455
Access Level:acceso abierto
Palabra clave:Gastrointestinal Neoplasms
Biomarkers, Tumor
MicroRNAs
Neoplasias Gastrointestinales
Biomarcadores de Tumor
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spelling Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancerValladares Ayerbes, ManuelHaz Conde, María del MarBlanco Calvo, MoisésAntón Aparicio, Luis MiguelFigueroa Conde-Valvís, AngélicaCalvo Martínez, LourdesGastrointestinal NeoplasmsBiomarkers, TumorMicroRNAsNeoplasias GastrointestinalesBiomarcadores de TumorMicroRNAsMicroRNAs (miRNAs) are small molecules of single strand non-coding RNAs, which are able to regulate gene expression. miRNAs have been involved in multiple cellular processes, such as proliferation, apoptosis and differentiation, thus alterations in miRNA expression have been shown to be directly linked with the pathological origin of multiple diseases, including cancer. In this way, during last few years, an increasing number of exciting advances have contributed to the understanding of miRNA roles in cancer. Moreover, researchers have exploited the special characteristics of miRNAs, such as the tissue and disease specificity or miRNA presence in blood, to explore their use as non-invasive tumour markers. In the present review, we summarize the current data on the potential usefulness of circulating miRNAs as diagnostic and prognostic tools in gastrointestinal tumours.2012info:eu-repo/semantics/articlehttp://hdl.handle.net/20.500.11940/7455reponame:RUNA. Repositorio da Consellería de Sanidade e Sergasinstname:Servizo Galego de Saúde (SERGAS)Ingléshttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:runa.sergas.gal:20.500.11940/74552026-06-12T08:40:47Z
dc.title.none.fl_str_mv Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancer
title Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancer
spellingShingle Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancer
Valladares Ayerbes, Manuel
Gastrointestinal Neoplasms
Biomarkers, Tumor
MicroRNAs
Neoplasias Gastrointestinales
Biomarcadores de Tumor
MicroRNAs
title_short Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancer
title_full Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancer
title_fullStr Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancer
title_full_unstemmed Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancer
title_sort Circulating MicroRNAs: Molecular microsensors in gastrointestinal cancer
dc.creator.none.fl_str_mv Valladares Ayerbes, Manuel
Haz Conde, María del Mar
Blanco Calvo, Moisés
Antón Aparicio, Luis Miguel
Figueroa Conde-Valvís, Angélica
Calvo Martínez, Lourdes
author Valladares Ayerbes, Manuel
author_facet Valladares Ayerbes, Manuel
Haz Conde, María del Mar
Blanco Calvo, Moisés
Antón Aparicio, Luis Miguel
Figueroa Conde-Valvís, Angélica
Calvo Martínez, Lourdes
author_role author
author2 Haz Conde, María del Mar
Blanco Calvo, Moisés
Antón Aparicio, Luis Miguel
Figueroa Conde-Valvís, Angélica
Calvo Martínez, Lourdes
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Gastrointestinal Neoplasms
Biomarkers, Tumor
MicroRNAs
Neoplasias Gastrointestinales
Biomarcadores de Tumor
MicroRNAs
topic Gastrointestinal Neoplasms
Biomarkers, Tumor
MicroRNAs
Neoplasias Gastrointestinales
Biomarcadores de Tumor
MicroRNAs
description MicroRNAs (miRNAs) are small molecules of single strand non-coding RNAs, which are able to regulate gene expression. miRNAs have been involved in multiple cellular processes, such as proliferation, apoptosis and differentiation, thus alterations in miRNA expression have been shown to be directly linked with the pathological origin of multiple diseases, including cancer. In this way, during last few years, an increasing number of exciting advances have contributed to the understanding of miRNA roles in cancer. Moreover, researchers have exploited the special characteristics of miRNAs, such as the tissue and disease specificity or miRNA presence in blood, to explore their use as non-invasive tumour markers. In the present review, we summarize the current data on the potential usefulness of circulating miRNAs as diagnostic and prognostic tools in gastrointestinal tumours.
publishDate 2012
dc.date.none.fl_str_mv 2012
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.11940/7455
url http://hdl.handle.net/20.500.11940/7455
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:RUNA. Repositorio da Consellería de Sanidade e Sergas
instname:Servizo Galego de Saúde (SERGAS)
instname_str Servizo Galego de Saúde (SERGAS)
reponame_str RUNA. Repositorio da Consellería de Sanidade e Sergas
collection RUNA. Repositorio da Consellería de Sanidade e Sergas
repository.name.fl_str_mv
repository.mail.fl_str_mv
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