Spray dried proliposomes of Rosmarinus officinalis polyphenols: a quality by design approach
[EN] Harnessing the benefits of rosemary polyphenols is limited by variability in their physicochemical properties. These limitations may be overcome by encapsulation in systems possessing hydro-lipophilic centers thereby accommodating molecules of different polarities. Proliposomes offer a viable o...
| Autores: | , , |
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| Tipo de recurso: | capítulo de libro |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universitat Politècnica de València (UPV) |
| Repositorio: | RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia |
| Idioma: | inglés |
| OAI Identifier: | oai:riunet.upv.es:10251/118576 |
| Acceso en línea: | https://riunet.upv.es/handle/10251/118576 |
| Access Level: | acceso abierto |
| Palabra clave: | Drying Dehydration Dewatering Emerging technologies Products quality Process control Environmental Evaporation Sublimation Diffusion Energy Intensification Polyphenols Antioxidant Proliposomes Spray drying |
| Sumario: | [EN] Harnessing the benefits of rosemary polyphenols is limited by variability in their physicochemical properties. These limitations may be overcome by encapsulation in systems possessing hydro-lipophilic centers thereby accommodating molecules of different polarities. Proliposomes offer a viable option in this regards, being particles which form liposomal suspension in water. Lyophilized extracts of rosemary was encapsulated in hydrogenatedsoyphosphatidylcholine/cholesterol by solvent replacement method. Spray dried proliposomes were obtained with lactose as carrier. Using Central Composite Design, the effects of lipid, extract and carrier concentrations on response variables including bioactive content and retention, moisture content characteristics, recuperation and redispersibility were evaluated by statistical analysis. |
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