Nanojet trapping of a single sub-10 nm upconverting nanoparticle in the full liquid water temperature range

Upconverting nanoparticles (UCNPs) have been used as optical probes in agreat variety of scenarios ranging from cells to animal models. When opti-cally trapped, a single UCNP can be remotely manipulated making possible, for instance, thermal scanning in the surroundings of a living cell. When conven...

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Detalles Bibliográficos
Autores: Lu, Dasheng, Pedroni, Marco, Labrador-Páez, Lucía, Marqués Ponce, Manuel Ignacio, Jaque García, Daniel, Haro González, Patricia
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/738700
Acceso en línea:https://hdl.handle.net/10486/738700
https://dx.doi.org/10.1002/smll.202006764
Access Level:acceso abierto
Palabra clave:Nanoparticles
optical trapping
photonic nanojet
thermal stability
upconversion
Física
Descripción
Sumario:Upconverting nanoparticles (UCNPs) have been used as optical probes in agreat variety of scenarios ranging from cells to animal models. When opti-cally trapped, a single UCNP can be remotely manipulated making possible, for instance, thermal scanning in the surroundings of a living cell. When conventional optics is used, the stability of an optically trapped UCNP is verylimited. Its reduced size leads to optical potentials comparable to thermalenergy, and up to now, stable optical trapping of a UCNP has been demon-strated only close to room temperature. This fact limits their use above roomtemperature, for instance, the use to investigate protein denaturalization thatoccurs in the 40–50 °C range. In this work, stable optical trapping of a single UCNP in the 20–90 °C range has been demonstrated by using a photonic nanojet. The use of an optically trapped microsphere makes it possible to overcome the diffraction limit producing another optical trap of smaller size and enhanced strength. This simple strategy leads not only to an improve-ment in the thermal stability of the optical trap but also to an enhancement of the emission intensity generated by the optically trapped UCNP