Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applications

In recent years great progress has been made in applying nanomaterials to design novel biosensors. Use of nanomaterials offers to biosensing platforms exceptional optical, electronic and magnetic properties. Nanomaterials can increase the surface of the transducing area of the sensors that in turn b...

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Detalles Bibliográficos
Autores: Kurbanoglu, Sevinc|||0000-0002-7079-7604, Ozkan, Sibel A., Merkoçi, Arben|||0000-0003-2486-8085
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:225318
Acceso en línea:https://ddd.uab.cat/record/225318
https://dx.doi.org/urn:doi:10.1016/j.bios.2016.09.102
Access Level:acceso abierto
Palabra clave:Nanomaterials
Enzyme
Biosensors
Enzyme inhibition
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spelling Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applicationsKurbanoglu, Sevinc|||0000-0002-7079-7604Ozkan, Sibel A.Merkoçi, Arben|||0000-0003-2486-8085NanomaterialsEnzymeBiosensorsEnzyme inhibitionIn recent years great progress has been made in applying nanomaterials to design novel biosensors. Use of nanomaterials offers to biosensing platforms exceptional optical, electronic and magnetic properties. Nanomaterials can increase the surface of the transducing area of the sensors that in turn bring an increase in catalytic behaviors. They have large surface-to-volume ratio, controlled morphology and structure that also favor miniaturization, an interesting advantage when the sample volume is a critical issue. Biosensors have great potential for achieving detect-to-protect devices: devices that can be used in detections of pollutants and other treating compounds/analytes (drugs) protecting citizens' life. After a long term focused scientific and financial efforts/supports biosensors are expected now to fulfill their promise such as being able to perform sampling and analysis of complex samples with interest for clinical or environment fields. Among all types of biosensors, enzymatic biosensors, the most explored biosensing devices, have an interesting property, the inherent inhibition phenomena given the enzyme-substrate complex formation. The exploration of such phenomena is making remarkably important their application as research and applied tools in diagnostics. Different inhibition biosensor systems based on nanomaterials modification has been proposed and applied. The role of nanomaterials in inhibition-based biosensors for the analyses of different groups of drugs as well as contaminants such as pesticides, phenolic compounds and others, are discussed in this review. This deep analysis of inhibition-based biosensors that employ nanomaterials will serve researchers as a guideline for further improvements and approaching of these devices to real sample applications so as to reach society needs and such biosensor market demands. 22017-01-0120172017-01-01Articlehttp://purl.org/coar/resource_type/c_6501AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/225318https://dx.doi.org/urn:doi:10.1016/j.bios.2016.09.102reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengAgència de Gestió d'Ajuts Universitaris i de Recerca https://doi.org/10.13039/501100003030 2014/SGR-260Ministerio de Economía y Competitividad https://doi.org/10.13039/501100003329 SEV-2013-0295Ministerio de Economía y Competitividad https://doi.org/10.13039/501100003329 MAT2014-52485-Popen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.https://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2253182026-06-06T12:50:31Z
dc.title.none.fl_str_mv Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applications
title Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applications
spellingShingle Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applications
Kurbanoglu, Sevinc|||0000-0002-7079-7604
Nanomaterials
Enzyme
Biosensors
Enzyme inhibition
title_short Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applications
title_full Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applications
title_fullStr Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applications
title_full_unstemmed Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applications
title_sort Nanomaterials-based enzyme electrochemical biosensors operating through inhibition for biosensing applications
dc.creator.none.fl_str_mv Kurbanoglu, Sevinc|||0000-0002-7079-7604
Ozkan, Sibel A.
Merkoçi, Arben|||0000-0003-2486-8085
author Kurbanoglu, Sevinc|||0000-0002-7079-7604
author_facet Kurbanoglu, Sevinc|||0000-0002-7079-7604
Ozkan, Sibel A.
Merkoçi, Arben|||0000-0003-2486-8085
author_role author
author2 Ozkan, Sibel A.
Merkoçi, Arben|||0000-0003-2486-8085
author2_role author
author
dc.subject.none.fl_str_mv Nanomaterials
Enzyme
Biosensors
Enzyme inhibition
topic Nanomaterials
Enzyme
Biosensors
Enzyme inhibition
description In recent years great progress has been made in applying nanomaterials to design novel biosensors. Use of nanomaterials offers to biosensing platforms exceptional optical, electronic and magnetic properties. Nanomaterials can increase the surface of the transducing area of the sensors that in turn bring an increase in catalytic behaviors. They have large surface-to-volume ratio, controlled morphology and structure that also favor miniaturization, an interesting advantage when the sample volume is a critical issue. Biosensors have great potential for achieving detect-to-protect devices: devices that can be used in detections of pollutants and other treating compounds/analytes (drugs) protecting citizens' life. After a long term focused scientific and financial efforts/supports biosensors are expected now to fulfill their promise such as being able to perform sampling and analysis of complex samples with interest for clinical or environment fields. Among all types of biosensors, enzymatic biosensors, the most explored biosensing devices, have an interesting property, the inherent inhibition phenomena given the enzyme-substrate complex formation. The exploration of such phenomena is making remarkably important their application as research and applied tools in diagnostics. Different inhibition biosensor systems based on nanomaterials modification has been proposed and applied. The role of nanomaterials in inhibition-based biosensors for the analyses of different groups of drugs as well as contaminants such as pesticides, phenolic compounds and others, are discussed in this review. This deep analysis of inhibition-based biosensors that employ nanomaterials will serve researchers as a guideline for further improvements and approaching of these devices to real sample applications so as to reach society needs and such biosensor market demands.
publishDate 2017
dc.date.none.fl_str_mv 2
2017-01-01
2017
2017-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/225318
https://dx.doi.org/urn:doi:10.1016/j.bios.2016.09.102
url https://ddd.uab.cat/record/225318
https://dx.doi.org/urn:doi:10.1016/j.bios.2016.09.102
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Agència de Gestió d'Ajuts Universitaris i de Recerca https://doi.org/10.13039/501100003030 2014/SGR-260
Ministerio de Economía y Competitividad https://doi.org/10.13039/501100003329 SEV-2013-0295
Ministerio de Economía y Competitividad https://doi.org/10.13039/501100003329 MAT2014-52485-P
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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