Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean Area

The Amaranthaceae family is composed of about 180 genera and 2500 species. These common weeds have become increasingly relevant as triggers of allergy in the last few years, as they are able to rapidly colonize salty and arid soils in extensive desert areas. The genera Chenopodium, Salsola, and Amar...

Descripción completa

Detalles Bibliográficos
Autores: Villalba, Mayte, Barderas Manchado, Rodrigo, Mas, S., Colás, S., Batanero Cremades, Eva, Rodríguez García, Rosalía
Tipo de recurso: artículo
Fecha de publicación:2014
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/34915
Acceso en línea:https://hdl.handle.net/20.500.14352/34915
Access Level:acceso abierto
Palabra clave:577.1
616-056.3
Pollinosis. Amaranthaceae. Recombinant allergen. Cross-reactivity
Polinosis. Amaranthaceae. Alérgeno recombinante. Reactividad cruzada
Alergología
Bioquímica (Medicina)
3207.01 Alergias
id ES_3f37320f80d0f3fbc6febb454392dc91
oai_identifier_str oai:docta.ucm.es:20.500.14352/34915
network_acronym_str ES
network_name_str España
repository_id_str
spelling Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean AreaVillalba, MayteBarderas Manchado, RodrigoMas, S.Colás, S.Batanero Cremades, EvaRodríguez García, Rosalía577.1616-056.3Pollinosis. Amaranthaceae. Recombinant allergen. Cross-reactivityPolinosis. Amaranthaceae. Alérgeno recombinante. Reactividad cruzadaAlergologíaBioquímica (Medicina)3207.01 AlergiasThe Amaranthaceae family is composed of about 180 genera and 2500 species. These common weeds have become increasingly relevant as triggers of allergy in the last few years, as they are able to rapidly colonize salty and arid soils in extensive desert areas. The genera Chenopodium, Salsola, and Amaranthus are the major sources of pollinosis from the Amaranthaceae family in southern Europe, western United States, and semidesert areas of Saudi Arabia, Kuwait, and Iran. In Spain, Salsola kali is one of the most relevant causes of pollinosis, together with olive and grasses. To date, 9 Amaranthaceae pollen allergens from Chenopodium album, Salsola kali, and Amaranthus retroflexus have been described and are listed in the International Union of Immunological Societies allergen nomenclature database. The major allergens of Amaranthaceae pollen belong to the pectin methylesterase, Ole e 1–like, and profilin panallergen families, whereas the minor allergens belong to the cobalaminindependent methionine synthase and polcalcin panallergen families. These relevant allergens have been characterized physicochemically, and immunologically at different levels. Recombinant forms, allergenic fusion recombinant proteins, and hypoallergenic derivatives of these allergens have been expressed in bacteria and yeast and compared with their natural proteins from pollen. In this review, we provide an extensive overview of Amaranthaceae pollen allergens, focusing on their physicochemical, and immunological properties and on their clinical significance in allergic patients. We also review studies where these recombinant allergens and their hypoallergenic derivatives have been used in clinical diagnosis and their potential use in personalized therapy.Esmon PublicidadUniversidad Complutense de Madrid20142014-01-0120142014-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/34915reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/349152026-06-02T12:44:21Z
dc.title.none.fl_str_mv Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean Area
title Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean Area
spellingShingle Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean Area
Villalba, Mayte
577.1
616-056.3
Pollinosis. Amaranthaceae. Recombinant allergen. Cross-reactivity
Polinosis. Amaranthaceae. Alérgeno recombinante. Reactividad cruzada
Alergología
Bioquímica (Medicina)
3207.01 Alergias
title_short Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean Area
title_full Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean Area
title_fullStr Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean Area
title_full_unstemmed Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean Area
title_sort Amaranthaceae Pollens: Review of an Emerging Allergy in the Mediterranean Area
dc.creator.none.fl_str_mv Villalba, Mayte
Barderas Manchado, Rodrigo
Mas, S.
Colás, S.
Batanero Cremades, Eva
Rodríguez García, Rosalía
author Villalba, Mayte
author_facet Villalba, Mayte
Barderas Manchado, Rodrigo
Mas, S.
Colás, S.
Batanero Cremades, Eva
Rodríguez García, Rosalía
author_role author
author2 Barderas Manchado, Rodrigo
Mas, S.
Colás, S.
Batanero Cremades, Eva
Rodríguez García, Rosalía
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 577.1
616-056.3
Pollinosis. Amaranthaceae. Recombinant allergen. Cross-reactivity
Polinosis. Amaranthaceae. Alérgeno recombinante. Reactividad cruzada
Alergología
Bioquímica (Medicina)
3207.01 Alergias
topic 577.1
616-056.3
Pollinosis. Amaranthaceae. Recombinant allergen. Cross-reactivity
Polinosis. Amaranthaceae. Alérgeno recombinante. Reactividad cruzada
Alergología
Bioquímica (Medicina)
3207.01 Alergias
description The Amaranthaceae family is composed of about 180 genera and 2500 species. These common weeds have become increasingly relevant as triggers of allergy in the last few years, as they are able to rapidly colonize salty and arid soils in extensive desert areas. The genera Chenopodium, Salsola, and Amaranthus are the major sources of pollinosis from the Amaranthaceae family in southern Europe, western United States, and semidesert areas of Saudi Arabia, Kuwait, and Iran. In Spain, Salsola kali is one of the most relevant causes of pollinosis, together with olive and grasses. To date, 9 Amaranthaceae pollen allergens from Chenopodium album, Salsola kali, and Amaranthus retroflexus have been described and are listed in the International Union of Immunological Societies allergen nomenclature database. The major allergens of Amaranthaceae pollen belong to the pectin methylesterase, Ole e 1–like, and profilin panallergen families, whereas the minor allergens belong to the cobalaminindependent methionine synthase and polcalcin panallergen families. These relevant allergens have been characterized physicochemically, and immunologically at different levels. Recombinant forms, allergenic fusion recombinant proteins, and hypoallergenic derivatives of these allergens have been expressed in bacteria and yeast and compared with their natural proteins from pollen. In this review, we provide an extensive overview of Amaranthaceae pollen allergens, focusing on their physicochemical, and immunological properties and on their clinical significance in allergic patients. We also review studies where these recombinant allergens and their hypoallergenic derivatives have been used in clinical diagnosis and their potential use in personalized therapy.
publishDate 2014
dc.date.none.fl_str_mv 2014
2014-01-01
2014
2014-01-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/34915
url https://hdl.handle.net/20.500.14352/34915
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Esmon Publicidad
publisher.none.fl_str_mv Esmon Publicidad
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869406618423132160
score 15,300719

Similares en LA Referencia