Dynamical task switching in cellular computers

We present a scheme for implementing a version of task switching in engineered bacteria, based on the manipulation of plasmid copy numbers. Our method allows for the embedding of multiple computations in a cellular population, whilst minimising resource usage inefficiency. We describe the results of...

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Detalles Bibliográficos
Autores: Goñi-Moreno, Angel, Cruz, Fernando de la|||0000-0003-4758-6857, Rodríguez-Patón, Alfonso, Amos, Martyn
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Universidad de Cantabria (UC)
Repositorio:UCrea Repositorio Abierto de la Universidad de Cantabria
Idioma:inglés
OAI Identifier:oai:repositorio.unican.es:10902/15868
Acceso en línea:http://hdl.handle.net/10902/15868
Access Level:acceso abierto
Palabra clave:Synthetic Biology
Cellular Computing
Plasmids
Descripción
Sumario:We present a scheme for implementing a version of task switching in engineered bacteria, based on the manipulation of plasmid copy numbers. Our method allows for the embedding of multiple computations in a cellular population, whilst minimising resource usage inefficiency. We describe the results of computational simulations of our model, and discuss the potential for future work in this area.