Timing evaluation of a PET detector block based on semi-monolithic LYSO crystals

[Purpose] Detectors for positron emission tomography (PET) typically use two types of scintillation crystals, pixelated or monolithic. A variant of these types of scintillators are the so-called semi-monolithic crystals. They consist of a monolithic crystal segmented in one direction in pieces calle...

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Detalhes bibliográficos
Autores: Cucarella, Neus, Barrio Toala, J., Lamprou, Efthymios, Valladares, Celia, Benlloch Baviera, José María, González Martínez, Antonio Javier
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2021
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/420033
Acesso em linha:http://hdl.handle.net/10261/420033
https://api.elsevier.com/content/abstract/scopus_id/85119590208
Access Level:Acceso aberto
Palavra-chave:PET
SiPMs
TOF-PET
Semi-monolithic scintillator crystals
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spelling Timing evaluation of a PET detector block based on semi-monolithic LYSO crystalsCucarella, NeusBarrio Toala, J.Lamprou, EfthymiosValladares, CeliaBenlloch Baviera, José MaríaGonzález Martínez, Antonio JavierPETSiPMsTOF-PETSemi-monolithic scintillator crystals[Purpose] Detectors for positron emission tomography (PET) typically use two types of scintillation crystals, pixelated or monolithic. A variant of these types of scintillators are the so-called semi-monolithic crystals. They consist of a monolithic crystal segmented in one direction in pieces called slabs. These scintillators have the potential to successfully combine the benefits of pixelated and monolithic configurations, providing good timing and spatial resolutions as well as the capacity to decode the depth of interaction (DOI) information. In this work, the timing performance of a detector based on semi-monolithic crystals was studied in depth. The energy response was also evaluated.[Methods] The semi-monolithic detector consists of 1 × 24 LYSO slabs of 25.4 × 12 × 0.95 mm3 each. The bottom surface of the slabs is coupled to an array of 8 × 8 silicon photomultipliers (SiPMs) of 3 × 3 mm2 active area, 50 μm cell size and 3.2 mm pitch. The 64 output signals were independently readout by the TOFPET2 ASIC. In order to achieve the best coincidence time resolution (CTR), four different time walk corrections were tested. Additional work investigated the best method of combining the timestamps belonging to the same event.[Results] The resolvability of the slabs in the measured flood maps improves with the thickness of a light guide placed in between the scintillators and photosensors. The energy resolution does not change significantly with values as good as 13.7%. Regarding the CTR, values of 335.8, 363, 369.8, and 402.5 ps have been obtained for the whole detector for no light guide, 0.5, 1.0, and 1.5 mm thickness light guide cases, respectively. These values further improve to 276.1, 302.6, 305.6 and 336.2 ps, respectively, when energy-weighted averaging of timestamps is applied.[Conclusions] We have shown both an excellent timing resolution and good energy resolution for a PET detector based on semi-monolithic crystals. The use of light guides of different thicknesses does not significantly affect the energy resolution of the whole detector, but the timing capabilities slightly worsen with the increasing thickness of the light guide.This work has been supported by the European Research Council (ERC) under the European Union's Horizon 2020 Research and Innovation programme (grant agreement number: 695536). This work has also been supported by the USA National Institutes of Health (NIH) under grant number: 1R01EB029450-01.Peer reviewedWiley-VCHEuropean CommissionNational Institutes of Health (US)Cucarella, Neus [0000-0001-7604-8404]Barrio Toala, J. [0000-0001-5181-2146]Lamprou, Efthymios [0000-0003-1141-296X]Valladares, Celia [0000-0002-1089-4736]Benlloch Baviera, José María [0000-0001-6073-1436]González Martínez, Antonio Javier [0000-0001-6742-5626]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202620262021info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/420033https://api.elsevier.com/content/abstract/scopus_id/85119590208reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/EC/H2020/695536The underlying dataset has been published as supplementary material of the article in the publisher platform at DOI https://doi.org/10.1002/mp.15318https://doi.org/10.1002/mp.15318Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4200332026-05-22T06:33:51Z
dc.title.none.fl_str_mv Timing evaluation of a PET detector block based on semi-monolithic LYSO crystals
title Timing evaluation of a PET detector block based on semi-monolithic LYSO crystals
spellingShingle Timing evaluation of a PET detector block based on semi-monolithic LYSO crystals
Cucarella, Neus
PET
SiPMs
TOF-PET
Semi-monolithic scintillator crystals
title_short Timing evaluation of a PET detector block based on semi-monolithic LYSO crystals
title_full Timing evaluation of a PET detector block based on semi-monolithic LYSO crystals
title_fullStr Timing evaluation of a PET detector block based on semi-monolithic LYSO crystals
title_full_unstemmed Timing evaluation of a PET detector block based on semi-monolithic LYSO crystals
title_sort Timing evaluation of a PET detector block based on semi-monolithic LYSO crystals
dc.creator.none.fl_str_mv Cucarella, Neus
Barrio Toala, J.
Lamprou, Efthymios
Valladares, Celia
Benlloch Baviera, José María
González Martínez, Antonio Javier
author Cucarella, Neus
author_facet Cucarella, Neus
Barrio Toala, J.
Lamprou, Efthymios
Valladares, Celia
Benlloch Baviera, José María
González Martínez, Antonio Javier
author_role author
author2 Barrio Toala, J.
Lamprou, Efthymios
Valladares, Celia
Benlloch Baviera, José María
González Martínez, Antonio Javier
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv European Commission
National Institutes of Health (US)
Cucarella, Neus [0000-0001-7604-8404]
Barrio Toala, J. [0000-0001-5181-2146]
Lamprou, Efthymios [0000-0003-1141-296X]
Valladares, Celia [0000-0002-1089-4736]
Benlloch Baviera, José María [0000-0001-6073-1436]
González Martínez, Antonio Javier [0000-0001-6742-5626]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv PET
SiPMs
TOF-PET
Semi-monolithic scintillator crystals
topic PET
SiPMs
TOF-PET
Semi-monolithic scintillator crystals
description [Purpose] Detectors for positron emission tomography (PET) typically use two types of scintillation crystals, pixelated or monolithic. A variant of these types of scintillators are the so-called semi-monolithic crystals. They consist of a monolithic crystal segmented in one direction in pieces called slabs. These scintillators have the potential to successfully combine the benefits of pixelated and monolithic configurations, providing good timing and spatial resolutions as well as the capacity to decode the depth of interaction (DOI) information. In this work, the timing performance of a detector based on semi-monolithic crystals was studied in depth. The energy response was also evaluated.
publishDate 2021
dc.date.none.fl_str_mv 2021
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/420033
https://api.elsevier.com/content/abstract/scopus_id/85119590208
url http://hdl.handle.net/10261/420033
https://api.elsevier.com/content/abstract/scopus_id/85119590208
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/EC/H2020/695536
The underlying dataset has been published as supplementary material of the article in the publisher platform at DOI https://doi.org/10.1002/mp.15318
https://doi.org/10.1002/mp.15318
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley-VCH
publisher.none.fl_str_mv Wiley-VCH
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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