Advances in functionalization of bioresorbable nanomembranes and nanoparticles for their use in biomedicine

Bioresorbable nanomembranes (NMs) and nanoparticles (NPs) are powerful polymeric materials playing an important role in biomedicine, as they can effectively reduce infections and inflammatory clinical patient conditions due to their high biocompatibility, ability to physically interact with biomolec...

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Detalles Bibliográficos
Autores: Madhani Mohammed Sadhakathullah, Ahammed Hussain|||0000-0002-8703-0450, Paulo Mirasol, Sofia|||0000-0002-3802-8880, Torras Costa, Juan|||0000-0001-8737-7609, Armelín Diggroc, Elaine Aparecida|||0000-0002-0658-7696
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/394482
Acceso en línea:https://hdl.handle.net/2117/394482
https://dx.doi.org/10.3390/ijms241210312
Access Level:acceso abierto
Palabra clave:Polymers in medicine
Biomedical materials
Biomedical engineering
Bioresorbable polymers
Nanomembranes
Nanoparticles
Biomedical devices
Biomedical implants
Drug delivery
Polímers en medicina
Materials biomèdics
Enginyeria biomèdica
Àrees temàtiques de la UPC::Enginyeria química
Descripción
Sumario:Bioresorbable nanomembranes (NMs) and nanoparticles (NPs) are powerful polymeric materials playing an important role in biomedicine, as they can effectively reduce infections and inflammatory clinical patient conditions due to their high biocompatibility, ability to physically interact with biomolecules, large surface area, and low toxicity. In this review, the most common bioabsorbable materials such as those belonging to natural polymers and proteins for the manufacture of NMs and NPs are reviewed. In addition to biocompatibility and bioresorption, current methodology on surface functionalization is also revisited and the most recent applications are highlighted. Considering the most recent use in the field of biosensors, tethered lipid bilayers, drug delivery, wound dressing, skin regeneration, targeted chemotherapy and imaging/diagnostics, functionalized NMs and NPs have become one of the main pillars of modern biomedical applications.