Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.

In acute ST-segment elevation myocardial infarction (STEMI) late gadolinium enhancement (LGE) may underestimate segmental functional recovery. We evaluated the predictive value of cardiac magnetic resonance (CMR) feature-tracking (FT) for functional recovery and whether it incremented the value of L...

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Authors: Valente, FX, Gavara, J, Gutierrez, L, Rios-Navarro, C, Rello, P, Maymi, M, Fernandez-Galera, R, Monmeneu, JV, Sao-Aviles, A, Lopez-Lereu, MP, Gonzalez-Alujas, MT, Moratal, D, Cuellar, H, Barrabes, J, Otaegui, I, Evangelista, A, Ferreira, I, Bodi, V, Rodriguez-Palomares, J
Format: article
Status:Published version
Publication Date:2021
Country:España
Institution:INCLIVA
Repository:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
OAI Identifier:oai:incliva.fundanetsuite.com:p16359
Online Access:https://incliva.portalinvestigacion.com/publicaciones/16359
Access Level:Open access
Keyword:acute ST-segment elevation myocardial infarction
cardiac magnetic resonance feature-tracking
low-dose dobutamine stress echocardiography
myocardial deformation
speckle-tracking echocardiography
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spelling Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.Valente, FXGavara, JGutierrez, LRios-Navarro, CRello, PMaymi, MFernandez-Galera, RMonmeneu, JVSao-Aviles, ALopez-Lereu, MPGonzalez-Alujas, MTMoratal, DCuellar, HBarrabes, JOtaegui, IEvangelista, AFerreira, IBodi, VRodriguez-Palomares, Jacute ST-segment elevation myocardial infarctioncardiac magnetic resonance feature-trackinglow-dose dobutamine stress echocardiographymyocardial deformationspeckle-tracking echocardiographyIn acute ST-segment elevation myocardial infarction (STEMI) late gadolinium enhancement (LGE) may underestimate segmental functional recovery. We evaluated the predictive value of cardiac magnetic resonance (CMR) feature-tracking (FT) for functional recovery and whether it incremented the value of LGE compared to low-dose dobutamine stress echocardiography (LDDSE) and speckle-tracking echocardiography (STE). Eighty patients underwent LDDSE and CMR within 5-7 days after STEMI and segmental functional recovery was defined as improvement in wall-motion at 6-months CMR. Optimal conventional and FT parameters were analyzed and then also applied to an external validation cohort of 222 STEMI patients. Circumferential strain (CS) was the strongest CMR-FT predictor and addition to LGE increased the overall accuracy to 74% and was especially relevant in segments with 50-74% LGE (AUC 0.60 vs. 0.75, p = 0.001). LDDSE increased the overall accuracy to 71%, and in the 50-74% LGE subgroup improved the AUC from 0.60 to 0.69 (p = 0.039). LGE + CS showed similar value as LGE + LDDSE. In the validation cohort, CS was also the strongest CMR-FT predictor of recovery and addition of CS to LGE improved overall accuracy to 73% although this difference was not significant (AUC 0.69, p = 0.44). Conclusion: CS is the strongest CMR-FT predictor of segmental functional recovery after STEMI. Its incremental value to LGE is comparable to that of LDDSE whilst avoiding an inotropic stress agent. CS is especially relevant in segments with 50-74% LGE where accuracy is lower and further testing is frequently required to clarify the potential for recovery.MDPI2021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://incliva.portalinvestigacion.com/publicaciones/16359Journal of Clinical MedicineISSN: 20770383reponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVAinstname:INCLIVAInglésinfo:eu-repo/semantics/openAccessoai:incliva.fundanetsuite.com:p163592026-06-07T16:35:31Z
dc.title.none.fl_str_mv Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.
title Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.
spellingShingle Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.
Valente, FX
acute ST-segment elevation myocardial infarction
cardiac magnetic resonance feature-tracking
low-dose dobutamine stress echocardiography
myocardial deformation
speckle-tracking echocardiography
title_short Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.
title_full Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.
title_fullStr Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.
title_full_unstemmed Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.
title_sort Predictive Value of Cardiac Magnetic Resonance Feature Tracking after Acute Myocardial Infarction: A Comparison with Dobutamine Stress Echocardiography.
dc.creator.none.fl_str_mv Valente, FX
Gavara, J
Gutierrez, L
Rios-Navarro, C
Rello, P
Maymi, M
Fernandez-Galera, R
Monmeneu, JV
Sao-Aviles, A
Lopez-Lereu, MP
Gonzalez-Alujas, MT
Moratal, D
Cuellar, H
Barrabes, J
Otaegui, I
Evangelista, A
Ferreira, I
Bodi, V
Rodriguez-Palomares, J
author Valente, FX
author_facet Valente, FX
Gavara, J
Gutierrez, L
Rios-Navarro, C
Rello, P
Maymi, M
Fernandez-Galera, R
Monmeneu, JV
Sao-Aviles, A
Lopez-Lereu, MP
Gonzalez-Alujas, MT
Moratal, D
Cuellar, H
Barrabes, J
Otaegui, I
Evangelista, A
Ferreira, I
Bodi, V
Rodriguez-Palomares, J
author_role author
author2 Gavara, J
Gutierrez, L
Rios-Navarro, C
Rello, P
Maymi, M
Fernandez-Galera, R
Monmeneu, JV
Sao-Aviles, A
Lopez-Lereu, MP
Gonzalez-Alujas, MT
Moratal, D
Cuellar, H
Barrabes, J
Otaegui, I
Evangelista, A
Ferreira, I
Bodi, V
Rodriguez-Palomares, J
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv acute ST-segment elevation myocardial infarction
cardiac magnetic resonance feature-tracking
low-dose dobutamine stress echocardiography
myocardial deformation
speckle-tracking echocardiography
topic acute ST-segment elevation myocardial infarction
cardiac magnetic resonance feature-tracking
low-dose dobutamine stress echocardiography
myocardial deformation
speckle-tracking echocardiography
description In acute ST-segment elevation myocardial infarction (STEMI) late gadolinium enhancement (LGE) may underestimate segmental functional recovery. We evaluated the predictive value of cardiac magnetic resonance (CMR) feature-tracking (FT) for functional recovery and whether it incremented the value of LGE compared to low-dose dobutamine stress echocardiography (LDDSE) and speckle-tracking echocardiography (STE). Eighty patients underwent LDDSE and CMR within 5-7 days after STEMI and segmental functional recovery was defined as improvement in wall-motion at 6-months CMR. Optimal conventional and FT parameters were analyzed and then also applied to an external validation cohort of 222 STEMI patients. Circumferential strain (CS) was the strongest CMR-FT predictor and addition to LGE increased the overall accuracy to 74% and was especially relevant in segments with 50-74% LGE (AUC 0.60 vs. 0.75, p = 0.001). LDDSE increased the overall accuracy to 71%, and in the 50-74% LGE subgroup improved the AUC from 0.60 to 0.69 (p = 0.039). LGE + CS showed similar value as LGE + LDDSE. In the validation cohort, CS was also the strongest CMR-FT predictor of recovery and addition of CS to LGE improved overall accuracy to 73% although this difference was not significant (AUC 0.69, p = 0.44). Conclusion: CS is the strongest CMR-FT predictor of segmental functional recovery after STEMI. Its incremental value to LGE is comparable to that of LDDSE whilst avoiding an inotropic stress agent. CS is especially relevant in segments with 50-74% LGE where accuracy is lower and further testing is frequently required to clarify the potential for recovery.
publishDate 2021
dc.date.none.fl_str_mv 2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://incliva.portalinvestigacion.com/publicaciones/16359
url https://incliva.portalinvestigacion.com/publicaciones/16359
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Journal of Clinical Medicine
ISSN: 20770383
reponame:r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname:INCLIVA
instname_str INCLIVA
reponame_str r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
collection r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869406503984693248
score 15,812455

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