Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing

Captive breeding programmes represent the most intensive type of ex situ population management for threatened species. One example is the Cuvier’s gazelle programme that started in 1975 with only four founding individuals, and after more than four decades of management in captivity, a reintroduction...

ver descrição completa

Detalhes bibliográficos
Autores: Alvarez-Estape, Marina, Fontsere, Claudia, Serres-Armero, Aitor, Kuderna, Lukas F. K., Dobrynin, Pavel, Guidara, Héla, Pukazhenthi, Budhan S., Koepfli, Klaus-Peter, Marqués-Bonet, Tomàs, Moreno, Eulalia, Lizano, Esther
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/271802
Acesso em linha:http://hdl.handle.net/10261/271802
Access Level:acceso abierto
Palavra-chave:Captive breeding
Cuvier’s gazelle
Genomics
Inbreeding
Reintroduction
id ES_3e07dc2aa1bae832a004d4f64f27d914
oai_identifier_str oai:digital.csic.es:10261/271802
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
spellingShingle Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
Alvarez-Estape, Marina
Captive breeding
Cuvier’s gazelle
Genomics
Inbreeding
Reintroduction
title_short Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title_full Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title_fullStr Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title_full_unstemmed Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
title_sort Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencing
dc.creator.none.fl_str_mv Alvarez-Estape, Marina
Fontsere, Claudia
Serres-Armero, Aitor
Kuderna, Lukas F. K.
Dobrynin, Pavel
Guidara, Héla
Pukazhenthi, Budhan S.
Koepfli, Klaus-Peter
Marqués-Bonet, Tomàs
Moreno, Eulalia
Lizano, Esther
author Alvarez-Estape, Marina
author_facet Alvarez-Estape, Marina
Fontsere, Claudia
Serres-Armero, Aitor
Kuderna, Lukas F. K.
Dobrynin, Pavel
Guidara, Héla
Pukazhenthi, Budhan S.
Koepfli, Klaus-Peter
Marqués-Bonet, Tomàs
Moreno, Eulalia
Lizano, Esther
author_role author
author2 Fontsere, Claudia
Serres-Armero, Aitor
Kuderna, Lukas F. K.
Dobrynin, Pavel
Guidara, Héla
Pukazhenthi, Budhan S.
Koepfli, Klaus-Peter
Marqués-Bonet, Tomàs
Moreno, Eulalia
Lizano, Esther
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Rancho Santa Fe Foundation
Ministerio de Ciencia, Innovación y Universidades (España)
Smithsonian Institution
European Research Council
European Commission
Ministerio de Economía y Competitividad (España)
Agencia Estatal de Investigación (España)
Howard Hughes Medical Institute
Generalitat de Catalunya
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Captive breeding
Cuvier’s gazelle
Genomics
Inbreeding
Reintroduction
topic Captive breeding
Cuvier’s gazelle
Genomics
Inbreeding
Reintroduction
description Captive breeding programmes represent the most intensive type of ex situ population management for threatened species. One example is the Cuvier’s gazelle programme that started in 1975 with only four founding individuals, and after more than four decades of management in captivity, a reintroduction effort was undertaken in Tunisia in 2016, to establish a population in an area historically included within its range. Here, we aim to determine the genetic consequences of this reintroduction event by assessing the genetic diversity of the founder stock as well as of their descendants. We present the first whole-genome sequencing dataset of 30 Cuvier’s gazelles including captive-bred animals, animals born in Tunisia after a reintroduction and individuals from a genetically unrelated Moroccan population. Our analyses revealed no difference between the founder and the offspring cohorts in genome-wide heterozygosity and inbreeding levels, and in the amount and length of runs of homozygosity. The captive but unmanaged Moroccan gazelles have the lowest genetic diversity of all genomes analysed. Our findings demonstrate that the Cuvier’s gazelle captive breeding programme can serve as source populations for future reintroductions of this species. We believe that this study can serve as a starting point for global applications of genomics to the conservation plan of this species.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/271802
url http://hdl.handle.net/10261/271802
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
#PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/MICIU//PRE2018-083966
info:eu-repo/grantAgreement/EC/H2020/864203
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2017-86471-P
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CGL2017-82654-P
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PGC2018-097426-B-C22
The underlying dataset has been published as supplementary material of the article in the publisher platform at 10.1111/eva.13336
https://doi.org/10.1111/eva.13336
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv John Wiley & Sons
publisher.none.fl_str_mv John Wiley & Sons
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869406492381151232
spelling Insights from the rescue and breeding management of Cuvier’s gazelle (Gazella cuvieri) through whole-genome sequencingAlvarez-Estape, MarinaFontsere, ClaudiaSerres-Armero, AitorKuderna, Lukas F. K.Dobrynin, PavelGuidara, HélaPukazhenthi, Budhan S.Koepfli, Klaus-PeterMarqués-Bonet, TomàsMoreno, EulaliaLizano, EstherCaptive breedingCuvier’s gazelleGenomicsInbreedingReintroductionCaptive breeding programmes represent the most intensive type of ex situ population management for threatened species. One example is the Cuvier’s gazelle programme that started in 1975 with only four founding individuals, and after more than four decades of management in captivity, a reintroduction effort was undertaken in Tunisia in 2016, to establish a population in an area historically included within its range. Here, we aim to determine the genetic consequences of this reintroduction event by assessing the genetic diversity of the founder stock as well as of their descendants. We present the first whole-genome sequencing dataset of 30 Cuvier’s gazelles including captive-bred animals, animals born in Tunisia after a reintroduction and individuals from a genetically unrelated Moroccan population. Our analyses revealed no difference between the founder and the offspring cohorts in genome-wide heterozygosity and inbreeding levels, and in the amount and length of runs of homozygosity. The captive but unmanaged Moroccan gazelles have the lowest genetic diversity of all genomes analysed. Our findings demonstrate that the Cuvier’s gazelle captive breeding programme can serve as source populations for future reintroductions of this species. We believe that this study can serve as a starting point for global applications of genomics to the conservation plan of this species.K-P. Koepfli and B. Pukazhenthi acknowledge the Sichel Endowment Fund for research support on dama gazelle genomics. M.A.E. is supported by an FPI (Formación de Personal Investigador) PRE2018-083966 from Ministerio de Ciencia, Universidades e Investigación. P.D. was supported as a postdoctoral fellow by the Smithsonian Institution Fellowship Program. K.-P.K. was supported by funding from the Smithsonian Institution's George E. Burch Fellowship in Theoretical Medicine and Affiliated Theoretical Science. T.M.-B. is supported by funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 864203), BFU2017-86471-P (MINECO/FEDER, UE), ‘Unidad de Excelencia María de Maeztu’, funded by the AEI (CEX2018-000792-M), Howard Hughes International Early Career and Secretaria d’Universitats i Recerca and CERCA Programme del Departament d’Economia i Coneixement de la Generalitat de Catalunya (GRC 2017 SGR 880). E.M. received financial support from the project PGC2018-097426-B-C22 (Spanish Ministry of Universities. Spanish State Research Agency. FEDER Program, European Union). E.L. is supported by CGL2017-82654-P (MINECO/FEDER, UE).Peer reviewedJohn Wiley & SonsRancho Santa Fe FoundationMinisterio de Ciencia, Innovación y Universidades (España)Smithsonian InstitutionEuropean Research CouncilEuropean CommissionMinisterio de Economía y Competitividad (España)Agencia Estatal de Investigación (España)Howard Hughes Medical InstituteGeneralitat de CatalunyaConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202220222022info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/271802reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MICIU//PRE2018-083966info:eu-repo/grantAgreement/EC/H2020/864203info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2017-86471-Pinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CGL2017-82654-Pinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PGC2018-097426-B-C22The underlying dataset has been published as supplementary material of the article in the publisher platform at 10.1111/eva.13336https://doi.org/10.1111/eva.13336Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2718022026-05-22T06:33:51Z
score 15.198674

Registos relacionados