Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compounds

Background: Walnuts (Juglans regia L.) are attracting increasing interest from consumers, industry, and the healthcare community due to their high content of bioactive compounds, including (poly)phenols, carotenoids, tocopherols, and omega-3 fatty acids. Despite the continued growth in global walnut...

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Autores: Campins Machado, Francesc Miquel, Abarca-Rivas, Clara, Corrado, Marina, Pérez Bosch, Maria, Vallverdú i Queralt, Anna
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2026
País:España
Recursos:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:dnet:ubarcelona__::7614253c5bdc0c052a6101fa5805f683
Acesso em linha:https://hdl.handle.net/2445/229186
Access Level:acceso abierto
Palavra-chave:Cuina (Nous)
Fruita seca
Polifenols
Compostos bioactius
Cooking (Nuts)
Dried fruit
Polyphenols
Bioactive compounds
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spelling Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compoundsCampins Machado, Francesc MiquelAbarca-Rivas, ClaraCorrado, MarinaPérez Bosch, MariaVallverdú i Queralt, AnnaCuina (Nous)Fruita secaPolifenolsCompostos bioactiusCooking (Nuts)Dried fruitPolyphenolsBioactive compoundsBackground: Walnuts (Juglans regia L.) are attracting increasing interest from consumers, industry, and the healthcare community due to their high content of bioactive compounds, including (poly)phenols, carotenoids, tocopherols, and omega-3 fatty acids. Despite the continued growth in global walnut production, the effective valorisation of walnut processing by-products remains a challenge. While most research has focused on the edible kernel, emerging evidence suggests that underutilized walnut fractions may also represent valuable sources of compounds with antioxidant and anti-inflammatory properties. This study aimed to characterize the bioactive compound profiles of green walnuts, defective walnuts, and walnut shells in comparison to commercial whole walnuts and kernels. Methods: Samples collected from an orchard located in Huesca (Spain) were homogenized and analysed in triplicate. Proximate composition was performed following the official methods, fatty acid profile was determined by GC-FID, phenolic profile by UHPLC-ESI-MS/MS, and carotenoids and tocopherols by UPLC-DAD. Results: Green walnuts contained exceptionally high concentrations of carotenoids, especially β-carotene (629.7 ± 39.4 mg/kg). Walnut shells were the richest source of phenolic compounds, notably ellagic acid (713.3 ± 7.6 mg/kg) and catechin (71.9 ± 1.2 mg/kg). Tocopherols were mainly concentrated in the kernel, dominated by γ-tocopherol (226.9 ± 8.1 mg/kg), while defective walnuts showed a compositional profile similar to commercial walnuts. Conclusions: This comparative analysis highlights the significant potential of walnut processing by-products as sources of nutritionally relevant bioactive compounds. The findings support their valorisation as functional ingredients for agro-food and cosmetic applications within a circular economy framework.Royal Society of Chemistry2026info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/229186Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1039/d6fo00494fFood & Function, 2026, vol. 17, p. 3161-3171https://doi.org/10.1039/d6fo00494fcc by-nc (c) Campins-Machado, F. M. et al., 2026https://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:dnet:ubarcelona__::7614253c5bdc0c052a6101fa5805f6832026-05-27T06:46:51Z
dc.title.none.fl_str_mv Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compounds
title Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compounds
spellingShingle Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compounds
Campins Machado, Francesc Miquel
Cuina (Nous)
Fruita seca
Polifenols
Compostos bioactius
Cooking (Nuts)
Dried fruit
Polyphenols
Bioactive compounds
title_short Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compounds
title_full Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compounds
title_fullStr Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compounds
title_full_unstemmed Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compounds
title_sort Upcycling walnut (Juglans regia L.) by-products: Characterisation of nutritionally relevant bioactive compounds
dc.creator.none.fl_str_mv Campins Machado, Francesc Miquel
Abarca-Rivas, Clara
Corrado, Marina
Pérez Bosch, Maria
Vallverdú i Queralt, Anna
author Campins Machado, Francesc Miquel
author_facet Campins Machado, Francesc Miquel
Abarca-Rivas, Clara
Corrado, Marina
Pérez Bosch, Maria
Vallverdú i Queralt, Anna
author_role author
author2 Abarca-Rivas, Clara
Corrado, Marina
Pérez Bosch, Maria
Vallverdú i Queralt, Anna
author2_role author
author
author
author
dc.subject.none.fl_str_mv Cuina (Nous)
Fruita seca
Polifenols
Compostos bioactius
Cooking (Nuts)
Dried fruit
Polyphenols
Bioactive compounds
topic Cuina (Nous)
Fruita seca
Polifenols
Compostos bioactius
Cooking (Nuts)
Dried fruit
Polyphenols
Bioactive compounds
description Background: Walnuts (Juglans regia L.) are attracting increasing interest from consumers, industry, and the healthcare community due to their high content of bioactive compounds, including (poly)phenols, carotenoids, tocopherols, and omega-3 fatty acids. Despite the continued growth in global walnut production, the effective valorisation of walnut processing by-products remains a challenge. While most research has focused on the edible kernel, emerging evidence suggests that underutilized walnut fractions may also represent valuable sources of compounds with antioxidant and anti-inflammatory properties. This study aimed to characterize the bioactive compound profiles of green walnuts, defective walnuts, and walnut shells in comparison to commercial whole walnuts and kernels. Methods: Samples collected from an orchard located in Huesca (Spain) were homogenized and analysed in triplicate. Proximate composition was performed following the official methods, fatty acid profile was determined by GC-FID, phenolic profile by UHPLC-ESI-MS/MS, and carotenoids and tocopherols by UPLC-DAD. Results: Green walnuts contained exceptionally high concentrations of carotenoids, especially β-carotene (629.7 ± 39.4 mg/kg). Walnut shells were the richest source of phenolic compounds, notably ellagic acid (713.3 ± 7.6 mg/kg) and catechin (71.9 ± 1.2 mg/kg). Tocopherols were mainly concentrated in the kernel, dominated by γ-tocopherol (226.9 ± 8.1 mg/kg), while defective walnuts showed a compositional profile similar to commercial walnuts. Conclusions: This comparative analysis highlights the significant potential of walnut processing by-products as sources of nutritionally relevant bioactive compounds. The findings support their valorisation as functional ingredients for agro-food and cosmetic applications within a circular economy framework.
publishDate 2026
dc.date.none.fl_str_mv 2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/229186
url https://hdl.handle.net/2445/229186
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1039/d6fo00494f
Food & Function, 2026, vol. 17, p. 3161-3171
https://doi.org/10.1039/d6fo00494f
dc.rights.none.fl_str_mv cc by-nc (c) Campins-Machado, F. M. et al., 2026
https://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by-nc (c) Campins-Machado, F. M. et al., 2026
https://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Royal Society of Chemistry
publisher.none.fl_str_mv Royal Society of Chemistry
dc.source.none.fl_str_mv Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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