Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study

The aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During...

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Detalhes bibliográficos
Autores: Tyrovolas, Stefanos, Polychronopoulos, Evangelos, Mariolis, Anargiros, Piscopo, Suzanne, Valacchi, Giuseppe, Makri, Kornilia, Zeimbekis, Akis, Tyrovola, Dimitra, Bountziouka, Vassiliki, Gotsis, Efthimios, Metallinos, George, Tur, Josep Antoni, Matalas, Antonia Leda, Lionis, Christos, Haro Abad, Josep Maria, Panagiotakos, Demosthenes B.
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2017
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/125151
Acesso em linha:https://hdl.handle.net/2445/125151
Access Level:acceso abierto
Palavra-chave:Longevitat
Malalties cardiovasculars
Epidemiologia genètica
Longevity
Cardiovascular diseases
Genetic epidemiology
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spelling Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS studyTyrovolas, StefanosPolychronopoulos, EvangelosMariolis, AnargirosPiscopo, SuzanneValacchi, GiuseppeMakri, KorniliaZeimbekis, AkisTyrovola, DimitraBountziouka, VassilikiGotsis, EfthimiosMetallinos, GeorgeTur, Josep AntoniMatalas, Antonia LedaLionis, ChristosHaro Abad, Josep MariaPanagiotakos, Demosthenes B.LongevitatMalalties cardiovascularsEpidemiologia genèticaLongevityCardiovascular diseasesGenetic epidemiologyThe aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During 2005 to 2011, 2663 elders were voluntarily enrolled. A multidimensional successful aging index consisting of 10 components was used. Paternal and maternal longevity was defined as those older participants of whom both parents lived above the age of 90. The burden of CVD-related factors (CVD-RFs) was calculated as the total score of 4 major CVD-RFs (range 0-4). After adjustment, parental longevity was inversely associated with the burden of CVD-RFs ( P = .04). Moreover, parental longevity was positively associated with the older adults' successful aging score (β-coefficient [95% confidence interval]: .38 [0.06-0.71]). Parent's long living was revealed as an important factor for successful aging and for reduced CVD risk, suggesting that further research is needed in the genetic predisposition of longevity.SAGE Publications2018201820172018info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion26 p.application/pdfhttps://hdl.handle.net/2445/125151Articles publicats en revistes (Medicina)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1177/0003319716642140Angiology, 2017, vol. 68, num. 2, p. 124-131https://doi.org/10.1177/0003319716642140(c) Tyrovolas, Stefanos et al., 2017info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1251512026-05-29T05:05:01Z
dc.title.none.fl_str_mv Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study
title Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study
spellingShingle Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study
Tyrovolas, Stefanos
Longevitat
Malalties cardiovasculars
Epidemiologia genètica
Longevity
Cardiovascular diseases
Genetic epidemiology
title_short Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study
title_full Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study
title_fullStr Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study
title_full_unstemmed Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study
title_sort Is parental longevity associated with the cardiovascular risk and the successful aging of their offspring? Results from the multinational MEDIS study
dc.creator.none.fl_str_mv Tyrovolas, Stefanos
Polychronopoulos, Evangelos
Mariolis, Anargiros
Piscopo, Suzanne
Valacchi, Giuseppe
Makri, Kornilia
Zeimbekis, Akis
Tyrovola, Dimitra
Bountziouka, Vassiliki
Gotsis, Efthimios
Metallinos, George
Tur, Josep Antoni
Matalas, Antonia Leda
Lionis, Christos
Haro Abad, Josep Maria
Panagiotakos, Demosthenes B.
author Tyrovolas, Stefanos
author_facet Tyrovolas, Stefanos
Polychronopoulos, Evangelos
Mariolis, Anargiros
Piscopo, Suzanne
Valacchi, Giuseppe
Makri, Kornilia
Zeimbekis, Akis
Tyrovola, Dimitra
Bountziouka, Vassiliki
Gotsis, Efthimios
Metallinos, George
Tur, Josep Antoni
Matalas, Antonia Leda
Lionis, Christos
Haro Abad, Josep Maria
Panagiotakos, Demosthenes B.
author_role author
author2 Polychronopoulos, Evangelos
Mariolis, Anargiros
Piscopo, Suzanne
Valacchi, Giuseppe
Makri, Kornilia
Zeimbekis, Akis
Tyrovola, Dimitra
Bountziouka, Vassiliki
Gotsis, Efthimios
Metallinos, George
Tur, Josep Antoni
Matalas, Antonia Leda
Lionis, Christos
Haro Abad, Josep Maria
Panagiotakos, Demosthenes B.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Longevitat
Malalties cardiovasculars
Epidemiologia genètica
Longevity
Cardiovascular diseases
Genetic epidemiology
topic Longevitat
Malalties cardiovasculars
Epidemiologia genètica
Longevity
Cardiovascular diseases
Genetic epidemiology
description The aim of the present study was to evaluate the role of parental longevity and parental cardiovascular disease (CVD) history in CVD risk and successful aging of a random sample of older adults living in the Mediterranean basin and who participated in the MEDiterranean Islands (MEDIS) study. During 2005 to 2011, 2663 elders were voluntarily enrolled. A multidimensional successful aging index consisting of 10 components was used. Paternal and maternal longevity was defined as those older participants of whom both parents lived above the age of 90. The burden of CVD-related factors (CVD-RFs) was calculated as the total score of 4 major CVD-RFs (range 0-4). After adjustment, parental longevity was inversely associated with the burden of CVD-RFs ( P = .04). Moreover, parental longevity was positively associated with the older adults' successful aging score (β-coefficient [95% confidence interval]: .38 [0.06-0.71]). Parent's long living was revealed as an important factor for successful aging and for reduced CVD risk, suggesting that further research is needed in the genetic predisposition of longevity.
publishDate 2017
dc.date.none.fl_str_mv 2017
2018
2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/125151
url https://hdl.handle.net/2445/125151
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1177/0003319716642140
Angiology, 2017, vol. 68, num. 2, p. 124-131
https://doi.org/10.1177/0003319716642140
dc.rights.none.fl_str_mv (c) Tyrovolas, Stefanos et al., 2017
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Tyrovolas, Stefanos et al., 2017
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 26 p.
application/pdf
dc.publisher.none.fl_str_mv SAGE Publications
publisher.none.fl_str_mv SAGE Publications
dc.source.none.fl_str_mv Articles publicats en revistes (Medicina)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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