The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review

Background: To know the medical documentation related to exogenous melatonin in sleep disorders caused by shift work in health personnel. Methods: Systematic and critical review. Data were obtained by looking up the bibliographic data base: MEDLINE (via Pubmed), Embase, Cochrane Library, Scopus, Web...

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Detalles Bibliográficos
Autores: Carriedo-Diez, Bárbara, Tosoratto-Venturi, Javier Lucas, Cantón-Manzano, Carmen, Wanden-Berghe, Carmina, Sanz-Valero, Javier
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/15062
Acceso en línea:http://hdl.handle.net/20.500.12105/15062
Access Level:acceso abierto
Palabra clave:Disorders of Excessive Somnolence
Melatonin
Sleep Disorders, Circadian Rhythm
Sleep Wake Disorders
Adult
Circadian Rhythm
Humans
Sleep
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spelling The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic ReviewCarriedo-Diez, BárbaraTosoratto-Venturi, Javier LucasCantón-Manzano, CarmenWanden-Berghe, CarminaSanz-Valero, JavierDisorders of Excessive SomnolenceMelatoninSleep Disorders, Circadian RhythmSleep Wake DisordersAdultCircadian RhythmHumansSleepBackground: To know the medical documentation related to exogenous melatonin in sleep disorders caused by shift work in health personnel. Methods: Systematic and critical review. Data were obtained by looking up the bibliographic data base: MEDLINE (via Pubmed), Embase, Cochrane Library, Scopus, Web of Science, Latin American and Caribbean literature in Health Sciences (LILACS) and Medicine in Spanish (MEDES). The used terms, as descriptors and text in the title and abstract record fields, were "Health Personnel", "Melatonin" and "Sleep Disorders", Circadian Rhythm, by using the following filters: "Humans", "Adult: 19+ years" and "Clinical Trial". The search update was in December 2021. The documentary quality of the articles was assessed using the CONSORT questionnaire. Results: Having applied the inclusion and exclusion criteria, 10 clinical essays were selected out of 98 retrieved references. CONSORT scores ranged from a minimum of 6.0 to a maximum of 13. 7 with a median of 10.2. According to the SIGN criteria, this review presented "1-"evidence with a grade of recommendation B. The intervention dose via administration of exogenous melatonin ranged between 1 and 10 mg. It was not mentioned whether the route of administration was by fast or slow absorption. The outcomes showed decreased daytime sleepiness, lessened sleep onset latency, diminished night-time awakenings, increased total sleep period and improved daytime attention in the melatonin-treated group. Conclusions: Exogenously administered melatonin is effective in shift worker health personnel that are suffering from sleep disorders, and given its low adverse effects and tolerability, it might be recommended. A great disparity was evidenced in terms of dose, follow-up periods and type of melatonin, small participant population, same age ranges and young age. Therefore, new trials would be needed to amend these observations in order to have full evidence that is able to ensure the efficacy of exogenous melatonin in the studied population.Multidisciplinary Digital Publishing Institute (MDPI)20222022-10-1820222022-08-1720222022-08-17review articlehttp://purl.org/coar/resource_type/c_dcae04bcVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/20.500.12105/15062reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/150622026-06-12T12:43:37Z
dc.title.none.fl_str_mv The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review
title The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review
spellingShingle The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review
Carriedo-Diez, Bárbara
Disorders of Excessive Somnolence
Melatonin
Sleep Disorders, Circadian Rhythm
Sleep Wake Disorders
Adult
Circadian Rhythm
Humans
Sleep
title_short The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review
title_full The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review
title_fullStr The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review
title_full_unstemmed The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review
title_sort The Effects of the Exogenous Melatonin on Shift Work Sleep Disorder in Health Personnel: A Systematic Review
dc.creator.none.fl_str_mv Carriedo-Diez, Bárbara
Tosoratto-Venturi, Javier Lucas
Cantón-Manzano, Carmen
Wanden-Berghe, Carmina
Sanz-Valero, Javier
author Carriedo-Diez, Bárbara
author_facet Carriedo-Diez, Bárbara
Tosoratto-Venturi, Javier Lucas
Cantón-Manzano, Carmen
Wanden-Berghe, Carmina
Sanz-Valero, Javier
author_role author
author2 Tosoratto-Venturi, Javier Lucas
Cantón-Manzano, Carmen
Wanden-Berghe, Carmina
Sanz-Valero, Javier
author2_role author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Disorders of Excessive Somnolence
Melatonin
Sleep Disorders, Circadian Rhythm
Sleep Wake Disorders
Adult
Circadian Rhythm
Humans
Sleep
topic Disorders of Excessive Somnolence
Melatonin
Sleep Disorders, Circadian Rhythm
Sleep Wake Disorders
Adult
Circadian Rhythm
Humans
Sleep
description Background: To know the medical documentation related to exogenous melatonin in sleep disorders caused by shift work in health personnel. Methods: Systematic and critical review. Data were obtained by looking up the bibliographic data base: MEDLINE (via Pubmed), Embase, Cochrane Library, Scopus, Web of Science, Latin American and Caribbean literature in Health Sciences (LILACS) and Medicine in Spanish (MEDES). The used terms, as descriptors and text in the title and abstract record fields, were "Health Personnel", "Melatonin" and "Sleep Disorders", Circadian Rhythm, by using the following filters: "Humans", "Adult: 19+ years" and "Clinical Trial". The search update was in December 2021. The documentary quality of the articles was assessed using the CONSORT questionnaire. Results: Having applied the inclusion and exclusion criteria, 10 clinical essays were selected out of 98 retrieved references. CONSORT scores ranged from a minimum of 6.0 to a maximum of 13. 7 with a median of 10.2. According to the SIGN criteria, this review presented "1-"evidence with a grade of recommendation B. The intervention dose via administration of exogenous melatonin ranged between 1 and 10 mg. It was not mentioned whether the route of administration was by fast or slow absorption. The outcomes showed decreased daytime sleepiness, lessened sleep onset latency, diminished night-time awakenings, increased total sleep period and improved daytime attention in the melatonin-treated group. Conclusions: Exogenously administered melatonin is effective in shift worker health personnel that are suffering from sleep disorders, and given its low adverse effects and tolerability, it might be recommended. A great disparity was evidenced in terms of dose, follow-up periods and type of melatonin, small participant population, same age ranges and young age. Therefore, new trials would be needed to amend these observations in order to have full evidence that is able to ensure the efficacy of exogenous melatonin in the studied population.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022-10-18
2022
2022-08-17
2022
2022-08-17
dc.type.none.fl_str_mv review article
http://purl.org/coar/resource_type/c_dcae04bc
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12105/15062
url http://hdl.handle.net/20.500.12105/15062
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
publisher.none.fl_str_mv Multidisciplinary Digital Publishing Institute (MDPI)
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,81155

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