Effects of a short-term resistance-training program on heart rate variability in children with cystic fibrosis: a randomized controlled trial

Background: Cystic fibrosis (CF) affects the autonomic nervous system (ANS) and exercise in healthy children modulates the interaction between sympathetic and parasympathetic activity. This study aimed to evaluate the effects of a short-term resistance exercise program on heart rate variability (HRV...

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Detalles Bibliográficos
Autores: Estévez-González, Agustín Jesús, Donadio, Marcio, Cobo-Vicente, Fernando, Fernández-Luna, Álvaro, Sanz-Santiago, Verónica, Villa Asensi, José Ramón, Iturriaga Ramirez, Tamara, Fernández-del-Valle, Maria, Diez-Vega, Ignacio, Larumbe-Zabala, Eneko, Pérez-Ruiz, Margarita
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:20.500.12328/2964
Acceso en línea:http://hdl.handle.net/20.500.12328/2964
https://dx.doi.org/10.3389/fphys.2021.652029
Access Level:acceso abierto
Palabra clave:Fibrosi quística
Sistema nerviós autònom
Activitat simpàtica
Activitat parasimpàtica
Fibrosis quística
Sistema nervioso autónomo
Actividad simpática
Actividad parasimpática
Cystic fibrosis
Autonomic nervous system
Friendly activity
Parasympathetic activity
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Descripción
Sumario:Background: Cystic fibrosis (CF) affects the autonomic nervous system (ANS) and exercise in healthy children modulates the interaction between sympathetic and parasympathetic activity. This study aimed to evaluate the effects of a short-term resistance exercise program on heart rate variability (HRV) in children and adolescents with CF. Methods: A randomized controlled trial was carried out in children diagnosed with CF aged 6–18 years. Individuals were divided into two groups: control (CON) and resistance-training (EX). Individuals in the EX group completed an individualized guided resistance program (5-RM—60–80%) for 8 weeks (3 sessions of 60 min/week). Upper and lower limbs exercises (seated bench press, seated lateral row, and leg press) were used. HRV was measured using a Suunto watch with subjects in lying position. Results: Nineteen subjects (13 boys) were included (CON = 11; and EX = 8). Mean age was 12.2 ± 3.3, FEV1 (forced expiratory volume in the first second) z-score was 1.72 ± 1.54 and peak oxygen consumption (VO2peak) 42.7 ± 7.4 mL.Kg–1.min–1. Exercise induced significant changes in the frequency-domain variables, including a decrease in LF power (p = 0.001, d = 0.98) and LF/HF ratio (p = 0.020, d = 0.92), and an increase in HF power (p = 0.001, d = −0.97), compared to the CON group. No significant changes were found for time-domain variables, although increases with a moderate effect size were seen for SDNN (p = 0.152, d = −0.41) and RMSSD (p = 0.059, d = −0.49) compared to the CON group. Conclusion: A short-term resistance exercise-training program was able to modulate HRV in children and adolescents with CF presenting mild to moderate lung function impairment and good physical condition.