Novel role of p73 as a regulator of developmental angiogenesis: implication for cancer therapy
[EN] Information regarding the role of p73 in the regulation of angiogenesis has been incomplete and quite controversial. Remarkably, several groups, including ours, have recently demonstrated that TP73 plays a fundamental role in angiogenesis regulation and that differential expression of TP73 coul...
| Autores: | , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2016 |
| País: | España |
| Institución: | Universidad de León |
| Repositorio: | BULERIA. Repositorio Institucional de la Universidad de León |
| OAI Identifier: | oai:buleria.unileon.es:10612/20498 |
| Acceso en línea: | https://www.tandfonline.com/doi/full/10.1080/23723556.2015.1019973 https://hdl.handle.net/10612/20498 |
| Access Level: | acceso abierto |
| Palabra clave: | Biología Medicina. Salud Angiogenesis Endothelial cell differentiation Endothelial cell migration Induced pluripotent stem cells Mouse embryonic stem cells p73 TGF-β Vasculogenesis 3207.03 Carcinogénesis 2407.02 Citogenética |
| Sumario: | [EN] Information regarding the role of p73 in the regulation of angiogenesis has been incomplete and quite controversial. Remarkably, several groups, including ours, have recently demonstrated that TP73 plays a fundamental role in angiogenesis regulation and that differential expression of TP73 could have important consequences in tumor angiogenesis. Here, we discuss a possible model for p73 function in the regulation of developmental angiogenesis and tumor angiogenesis |
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