Vaccinia Virus E3 Protein Prevents the Antiviral Action of ISG15

16 pages, 10 figures.-- PMID: 18604270 [PubMed].-- PMCID: PMC2434199.-- Supporting material available: Figure S1: Effect of ISG15 overexpression on virus citotoxicity after infection of MEFs with virulent and E3L deletion VACV mutant viruses. Table S1: Levels of ISG15 mRNA detected by quantitative r...

Descripción completa

Detalles Bibliográficos
Autores: Guerra, Susana, Cáceres, Ana, Knobeloch, Klaus-Peter, Horak, Ivan, Esteban, Mariano
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/8832
Acceso en línea:http://hdl.handle.net/10261/8832
Access Level:acceso abierto
Palabra clave:Vaccinia virus (VACV)
Type I interferons (IFN)
Immune response
Interferon-stimulated gene product 15 (ISG15)
Murine embryo fibroblast (MEFs)
Viral immune evasion mechanisms
Virus E3 protein
Poxviruses
Descripción
Sumario:16 pages, 10 figures.-- PMID: 18604270 [PubMed].-- PMCID: PMC2434199.-- Supporting material available: Figure S1: Effect of ISG15 overexpression on virus citotoxicity after infection of MEFs with virulent and E3L deletion VACV mutant viruses. Table S1: Levels of ISG15 mRNA detected by quantitative realtime RT-PCR after infection of HeLa cells with several VACV mutants.