The seroprevalence of human infection with Rickettsia slovaca, in an area of northern Spain

An epidemiological survey was undertaken to explore human exposure to Rickettsia slovaca in two provinces of northern Spain. When IFAT were used to test 200 members of the general population for antibodies to rickettsiae of the spotted-fever group, six (3.3%) were found positive, presumably, since D...

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Detalles Bibliográficos
Autores: Lledó García, María Lourdes|||0000-0001-5387-6792, Gegúndez Cámara, María Isabel|||0000-0003-4986-1605, Fernández, N., Sousa, Rita, Saz Pérez, José Vicente, Álamo, Rufino, Pérez Sánchez, R., Fernández Soto, Pedro, Bacellar, Fatima
Tipo de recurso: artículo
Fecha de publicación:2006
País:España
Institución:Universidad de Alcalá (UAH)
Repositorio:e_Buah Biblioteca Digital Universidad de Alcalá
Idioma:inglés
OAI Identifier:oai:ebuah.uah.es:10017/61156
Acceso en línea:http://hdl.handle.net/10017/61156
https://dx.doi.org/10.1179/136485906X105570
Access Level:acceso abierto
Palabra clave:Medicina
Medicine
Descripción
Sumario:An epidemiological survey was undertaken to explore human exposure to Rickettsia slovaca in two provinces of northern Spain. When IFAT were used to test 200 members of the general population for antibodies to rickettsiae of the spotted-fever group, six (3.3%) were found positive, presumably, since Dermacentor is one of the most common genera of human-biting tick in the study area, for antibodies to R. slovaca. Thirty-one (16.9%) of an additional 183 subjects who presented shortly after being bitten by ticks were also found seropositive. The difference in seroprevalence between the general and the tick-bitten populations was significant. Subject gender had no influence on seroprevalence in either population, although, in the tick-bitten group, age and occupation did have a significant influence on the prevalence recorded. Immunoblotting was used to confirm the presence of antibodies in the five subjects, all from the tick-bitten group, found to have acute infections. Three D. marginatus ticks obtained from three of these acute cases were found PCR-positive for R. slovaca DNA.