The fight against multidrug-resistant organisms: The role of ZnO crystalline defects

This article reports the excellent antimicrobial response of nanoparticulate ZnO against multidrug-resistant organisms (MDROs). We demonstrate that the enhanced antimicrobial activity against MDROs depends on the crystalline defects of ZnO. Hence, this work provides insights on the ZnO-microorganism...

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Detalles Bibliográficos
Autores: Lucas-Gil, Eva de, Campo, Ángel Adolfo del, Pascual, Laura, Monte-Serrano, Mercedes, Menéndez, Javier, Fernández Lozano, José Francisco, Rubio Marcos, Fernando
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/192135
Acceso en línea:http://hdl.handle.net/10261/192135
Access Level:acceso abierto
Palabra clave:Antimicrobial properties
MDROs, Action mechanisms
ZnO
Nanoparticles
Descripción
Sumario:This article reports the excellent antimicrobial response of nanoparticulate ZnO against multidrug-resistant organisms (MDROs). We demonstrate that the enhanced antimicrobial activity against MDROs depends on the crystalline defects of ZnO. Hence, this work provides insights on the ZnO-microorganism interactions, and we pose combined physico-chemical action mechanisms against resistant bacteria.