Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis
Background: Streptococcus tigurinus was recently described as a new streptococcal species within the viridans group streptococci (VGS). The objectives of the present work were to analyse the clinical and microbiological characteristics of S. tigurinus isolated from patients with bacteraemias, to det...
| Autores: | , , , , , , , , , , , , , , , , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2019 |
| País: | España |
| Recursos: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/171684 |
| Acesso em linha: | https://hdl.handle.net/2445/171684 |
| Access Level: | acceso abierto |
| Palavra-chave: | Endocarditis Diagnòstic Epidemiologia Infeccions Diagnosis Epidemiology Infections |
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Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditisErcibengoa, MaríaGoenaga Sánchez, Miguel ÁngelArdanuy Tisaire, María CarmenGrau, ImmaculadaGarcía de la Mària, CristinaAlmela, M. (Manel)Miró Meda, José M. (José María), 1956-Navas Pérez, EnriqueFariñas, María CarmenRuiz de Alegría, CarlosTorre, Javier de laFernández, FernandoMarín, MercedesMuñoz, PatriciaOrden, BeatrizOteo, José AntonioGarcía-Álvarez, LaraAlarcón, Aristides deLepe, José AntonioMarimón, José MaríaEndocarditisDiagnòsticEpidemiologiaInfeccionsEndocarditisDiagnosisEpidemiologyInfectionsBackground: Streptococcus tigurinus was recently described as a new streptococcal species within the viridans group streptococci (VGS). The objectives of the present work were to analyse the clinical and microbiological characteristics of S. tigurinus isolated from patients with bacteraemias, to determine the prevalence of S. tigurinus among VGS endocarditis in Spain, and to compare the clinical characteristics and outcomes of endocarditis caused by S. tigurinus and other VGS. Methods: retrospective nationwide study, performed between 2008 and 2016 in 9 Spanish hospitals from 7 different provinces comprising 237 cases of infective endocarditis. Streptococcal isolates were identified by sequencing fragments of their 16S rRNA, sodA and groEL genes. Clinical data of patients with streptococcal endocarditis were prospectively collected according to a pre-established protocol. Results: patients with endocarditis represented 7/9 (77.8%) and 26/86 (30.2%) of the bacteraemias caused by S. tigurinus and other VGS, respectively (p < 0.001), in two of the hospital participants. Among patients with streptococcal endocarditis, 12 different Streptococcus species were recognized being S. oralis, S. tigurinus and S. mitis the three more common. No relevant statistical differences were observed in the clinical characteristics and outcomes of endocarditis caused by the different VGS species. Conclusions: in this multicenter study performed in Spain, S. tigurinus showed a higher predilection for the endocardial endothelium as compared to other VGS. However, clinical characteristics and outcomes of endocarditis caused by S. tigurinus did not significantly differ from endocarditis caused by other oral streptococci.BioMed Central2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/171684Articles publicats en revistes (Patologia i Terapèutica Experimental)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1186/s12879-019-3914-6BMC Infectious Diseases, 2019, vol. 19, num. 1, p. 291https://doi.org/10.1186/s12879-019-3914-6cc-by (c) Ercibengoa, María et al., 2019http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1716842026-05-27T06:46:51Z |
| dc.title.none.fl_str_mv |
Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis |
| title |
Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis |
| spellingShingle |
Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis Ercibengoa, María Endocarditis Diagnòstic Epidemiologia Infeccions Endocarditis Diagnosis Epidemiology Infections |
| title_short |
Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis |
| title_full |
Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis |
| title_fullStr |
Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis |
| title_full_unstemmed |
Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis |
| title_sort |
Epidemiological and clinical characteristics of Streptococcus tigurinus endocarditis |
| dc.creator.none.fl_str_mv |
Ercibengoa, María Goenaga Sánchez, Miguel Ángel Ardanuy Tisaire, María Carmen Grau, Immaculada García de la Mària, Cristina Almela, M. (Manel) Miró Meda, José M. (José María), 1956- Navas Pérez, Enrique Fariñas, María Carmen Ruiz de Alegría, Carlos Torre, Javier de la Fernández, Fernando Marín, Mercedes Muñoz, Patricia Orden, Beatriz Oteo, José Antonio García-Álvarez, Lara Alarcón, Aristides de Lepe, José Antonio Marimón, José María |
| author |
Ercibengoa, María |
| author_facet |
Ercibengoa, María Goenaga Sánchez, Miguel Ángel Ardanuy Tisaire, María Carmen Grau, Immaculada García de la Mària, Cristina Almela, M. (Manel) Miró Meda, José M. (José María), 1956- Navas Pérez, Enrique Fariñas, María Carmen Ruiz de Alegría, Carlos Torre, Javier de la Fernández, Fernando Marín, Mercedes Muñoz, Patricia Orden, Beatriz Oteo, José Antonio García-Álvarez, Lara Alarcón, Aristides de Lepe, José Antonio Marimón, José María |
| author_role |
author |
| author2 |
Goenaga Sánchez, Miguel Ángel Ardanuy Tisaire, María Carmen Grau, Immaculada García de la Mària, Cristina Almela, M. (Manel) Miró Meda, José M. (José María), 1956- Navas Pérez, Enrique Fariñas, María Carmen Ruiz de Alegría, Carlos Torre, Javier de la Fernández, Fernando Marín, Mercedes Muñoz, Patricia Orden, Beatriz Oteo, José Antonio García-Álvarez, Lara Alarcón, Aristides de Lepe, José Antonio Marimón, José María |
| author2_role |
author author author author author author author author author author author author author author author author author author author |
| dc.subject.none.fl_str_mv |
Endocarditis Diagnòstic Epidemiologia Infeccions Endocarditis Diagnosis Epidemiology Infections |
| topic |
Endocarditis Diagnòstic Epidemiologia Infeccions Endocarditis Diagnosis Epidemiology Infections |
| description |
Background: Streptococcus tigurinus was recently described as a new streptococcal species within the viridans group streptococci (VGS). The objectives of the present work were to analyse the clinical and microbiological characteristics of S. tigurinus isolated from patients with bacteraemias, to determine the prevalence of S. tigurinus among VGS endocarditis in Spain, and to compare the clinical characteristics and outcomes of endocarditis caused by S. tigurinus and other VGS. Methods: retrospective nationwide study, performed between 2008 and 2016 in 9 Spanish hospitals from 7 different provinces comprising 237 cases of infective endocarditis. Streptococcal isolates were identified by sequencing fragments of their 16S rRNA, sodA and groEL genes. Clinical data of patients with streptococcal endocarditis were prospectively collected according to a pre-established protocol. Results: patients with endocarditis represented 7/9 (77.8%) and 26/86 (30.2%) of the bacteraemias caused by S. tigurinus and other VGS, respectively (p < 0.001), in two of the hospital participants. Among patients with streptococcal endocarditis, 12 different Streptococcus species were recognized being S. oralis, S. tigurinus and S. mitis the three more common. No relevant statistical differences were observed in the clinical characteristics and outcomes of endocarditis caused by the different VGS species. Conclusions: in this multicenter study performed in Spain, S. tigurinus showed a higher predilection for the endocardial endothelium as compared to other VGS. However, clinical characteristics and outcomes of endocarditis caused by S. tigurinus did not significantly differ from endocarditis caused by other oral streptococci. |
| publishDate |
2019 |
| dc.date.none.fl_str_mv |
2019 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/2445/171684 |
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https://hdl.handle.net/2445/171684 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Reproducció del document publicat a: https://doi.org/10.1186/s12879-019-3914-6 BMC Infectious Diseases, 2019, vol. 19, num. 1, p. 291 https://doi.org/10.1186/s12879-019-3914-6 |
| dc.rights.none.fl_str_mv |
cc-by (c) Ercibengoa, María et al., 2019 http://creativecommons.org/licenses/by/3.0/es info:eu-repo/semantics/openAccess |
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cc-by (c) Ercibengoa, María et al., 2019 http://creativecommons.org/licenses/by/3.0/es |
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openAccess |
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application/pdf |
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BioMed Central |
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BioMed Central |
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Articles publicats en revistes (Patologia i Terapèutica Experimental) reponame:Dipòsit Digital de la UB instname:Universidad de Barcelona |
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Universidad de Barcelona |
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Dipòsit Digital de la UB |
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Dipòsit Digital de la UB |
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