Adherence to mediterranean diet and the risk of differentiated thyroid cancer in a European cohort: The EPIC study

BackgroundThe Mediterranean diet (MD) has been proposed as a healthy diet with a potential to lower the incidence of several types of cancer, but there is no data regarding thyroid cancer (TC). We investigated the association between MD adherence, and its components, and the differentiated TC risk w...

Descripción completa

Detalles Bibliográficos
Autores: Llaha, Fjorida, Cayssials, Valerie, Farràs, Marta, Agudo, Antonio, Sandström, Maria, Eriksen, Anne Kirstine, Tjønneland, Anne, Boutron-Ruault, Marie-Christine, Laouali, Nasser, Truong, Thérèse, Le Cornet, Charlotte, Katzke, Verena, Schulze, Matthias B., Palli, Domenico, Krogh, Vittorio, Signoriello, Simona, Tumino, Rosario, Ricceri, Fulvio, Skeie, Guri, Jensen, Torill Miriam Enget, Chen, Sairah Lai Fa, Lasheras, Cristina, Rodriguez Barranco, Miguel, Amiano, Pilar, Huerta, José María, Guevara, Marcela, Almquist, Martin, Nilson, Lena Maria, Hennings, Joakim, Papier, Keren, Heath, Alicia K., Weiderpass, Elisabete, Rinaldi, Sabina, Zamora-Ros, Raul
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/189564
Acceso en línea:https://hdl.handle.net/2445/189564
Access Level:acceso abierto
Palabra clave:Cuina mediterrània
Càncer de tiroide
Mediterranean cooking
Thyroid gland cancer
Descripción
Sumario:BackgroundThe Mediterranean diet (MD) has been proposed as a healthy diet with a potential to lower the incidence of several types of cancer, but there is no data regarding thyroid cancer (TC). We investigated the association between MD adherence, and its components, and the differentiated TC risk within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. MethodsOver 450,000 men and women from nine European countries were followed up for a mean of 14.1 years, during which 712 differentiated TC cases were identified. Adherence to MD was estimated using the relative MD (rMED) score, an 18-point scale including alcohol, and the adapted rMED (arMED) score, a 16-point scale excluding alcohol. Hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using Cox regression models adjusted for potential confounding factors. ResultsAdherence to the arMED score was not associated with the risk of differentiated TC (HRhigh vs. low adherence = 0.94, 95% CI: 0.70-1.25; p-trend 0.27), while a suggestive, but non-statistically significant inverse relationship was observed with rMED (HRhigh vs. low adherence = 0.88, 95% CI: 0.68-1.14; p-trend 0.17). Low meat (HRlow vs. high meat intake = 0.81, 95% CI: 0.67-0.99; p-trend = 0.04) and moderate alcohol (HRmoderate vs. non-moderate intake = 0.88, 95% CI: 0.75-1.03) intake were related with lower differentiated TC risk. ConclusionsOur study shows that a high adherence to MD is not strongly related to differentiated TC risk, although further research is required to confirm the impact of MD and, especially, meat intake in TC risk.

Similares en LA Referencia