TMS suppression of right pars triangularis, but not pars opercularis, improves naming in aphasia [Author version]

This study sought to discover if an optimum 1 cm2 area in the non-damaged right hemisphere (RH) was present, which could temporarily improve naming in chronic, nonfluent aphasia patients when suppressed with repetitive transcranial magnetic stimulation (rTMS). Ten minutes of slow, 1 Hz rTMS was appl...

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Detalles Bibliográficos
Autores: Naeser, Margaret A., Martin, Paula I., Theoret, Hugo, Kobayashi, Masahito, Fregni, Felipe, Nicholas, Marjorie, Tormos Muñoz, José María, Steven, Megan S., Baker, Errol H., Pascual Leone, Álvaro
Tipo de recurso: artículo
Fecha de publicación:2012
País:España
Institución:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/3324
Acceso en línea:http://hdl.handle.net/20.500.12466/3324
Access Level:acceso abierto
Palabra clave:Transcranial magnetic stimulation (rTMS)
Brain stimulation
Aphasia
Stroke rehabilitation
2490 Neurociencias
3207.11 Neuropatología
Descripción
Sumario:This study sought to discover if an optimum 1 cm2 area in the non-damaged right hemisphere (RH) was present, which could temporarily improve naming in chronic, nonfluent aphasia patients when suppressed with repetitive transcranial magnetic stimulation (rTMS). Ten minutes of slow, 1 Hz rTMS was applied to suppress different RH ROIs in eight aphasia cases. Picture naming and response time (RT) were examined before, and immediately after rTMS. In aphasia patients, suppression of right pars triangularis (PTr) led to significant increase in pictures named, and significant decrease in RT. Suppression of right pars opercularis (POp), however, led to significant increase in RT, but no change in number of pictures named. Eight normals named all pictures correctly; similar to aphasia patients, RT significantly decreased following rTMS to suppress right PTr, versus right POp. Differential effects following suppression of right PTr versus right POp suggest different functional roles for these regions.

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