Neurocalcin immunoreactivity in the rato accessory olfactory bulb

The distribution and morphology of neurocalcin-immunopositive neurons have been studied in the rat accessory olfactory bulb. Different subsets of neurons displaying neurocalcin-immunoreactivity were found in the glomerular layer, the external plexiform layer and the internal plexiform layer. The mos...

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Detalles Bibliográficos
Autores: Porteros Herrero, Ángel Fernando, Briñón, Jesús G., Crespo, Carlos, Okazaki, Katsuo, Hidaka, Hirayosi, Aijón Noguera, José, Alonso Peña, José Ramón
Tipo de recurso: artículo
Fecha de publicación:1996
País:España
Institución:Universidad de Salamanca (USAL)
Repositorio:GREDOS. Repositorio Institucional de la Universidad de Salamanca
OAI Identifier:oai:gredos.usal.es:10366/116099
Acceso en línea:http://hdl.handle.net/10366/116099
http://dx.doi.org/10.1016/0006-8993(96)00416-7
Access Level:acceso abierto
Palabra clave:Accessory olfactory system
Calcium-binding protein
Immunohistochemistry
Neurocalcin
Rat
Vomeronasal organ
2490 Neurociencias
2490.02 Neuroquímica
Descripción
Sumario:The distribution and morphology of neurocalcin-immunopositive neurons have been studied in the rat accessory olfactory bulb. Different subsets of neurons displaying neurocalcin-immunoreactivity were found in the glomerular layer, the external plexiform layer and the internal plexiform layer. The most abundant staining was detected in the glomerular layer where neurocalcin-immunoreactive periglomerular cells and external tufted cells were observed in the lateral glomeruli, whereas the central region of this layer was practically devoid of immunopositive neurons. In the external plexiform layer, medial tufted cells and Van Gehuchten cells displayed neurocalcin-immunoreactivity. In the internal plexiform layer, interneurons classified as horizontal cells and vertical cells of Cajal were neurocalcin-immunostained. The staining pattern for neurocalcin in the accessory olfactory bulb showed similarities with the immunostaining described in this brain region for another EF-hand calcium binding protein, calbindin D-28k. However, after double immunohistochemical labeling, colocalization of both proteins in the same neuron was not observed, reflecting a biochemical heterogeneity within morphologically homogeneous neuronal groups.