Neuro-EPO by Nasal Route as a Neuroprotective Therapy in Brain Ischemia

Cerebral vascular diseases (CVD) are the third leading cause of death in industrialized countries and in Cuba affect the 50% of the population above 60 years old. The mortality is exponentially increased with age and doubles every five years. A total of 22,000 annual cases are estimated in Cuba, a c...

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Detalhes bibliográficos
Autores: García Rodríguez, Julio César, Rama Bretón, Ramón
Formato: capítulo de livro
Estado:Versión publicada
Fecha de publicación:2012
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/174405
Acesso em linha:https://hdl.handle.net/2445/174405
Access Level:acceso abierto
Palavra-chave:Isquèmia cerebral
Malalties cerebrovasculars
Cerebral ischemia
Cerebrovascular disease
Descrição
Resumo:Cerebral vascular diseases (CVD) are the third leading cause of death in industrialized countries and in Cuba affect the 50% of the population above 60 years old. The mortality is exponentially increased with age and doubles every five years. A total of 22,000 annual cases are estimated in Cuba, a country where life expectance should increase to 80 years in the near future [1]. CVD are often followed by a high social and individual cost as a consequence of disability and family affectation. The most problematic among such diseases is ischemic cerebral vascular disease, characterized by the reduction of cerebral blood flow (CBF) below a critical level. From this initial event several processes take place to induce the clinical symptoms of cerebral ischemia...