Gaps in clinical research in frontotemporal dementia

Frontotemporal dementia (FTD) is one of the leading causes of dementia before age 65 and often manifests as abnormal behavior (in behavioral variant FTD) or language impairment (in primary progressive aphasia). FTD's exact clinical presentation varies by culture, language, education, social nor...

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Detalles Bibliográficos
Autores: Franzen, Sanne, Nuytemans, Karen, Bourdage, Renelle, Caramelli, Paulo, Ellajosyula, Ratnavalli, Finger, Elizabeth, Illán-Gala, Ignacio|||0000-0002-5418-2052, Loi, Samantha M., Morhardt, Darby, Pijnenburg, Yolande|||0000-0003-2464-1905, Rascovsky, Katya, Williams, Monique M., Yokoyama, Jennifer S.|||0000-0001-7274-2634, Alladi, Suvarna, Ayhan, Yavuz, Broce, Iris|||0000-0003-4932-1430, Castro-Suarez, Sheila, Coleman, Kristy, de Souza, Leonardo Cruz, Dacks, Penny A., de Boer, Sterre C.M., de Leon, Jessica, Dodge, Shana, Grasso, Stephanie, Gupta, Veer, Ghoshal, Nupur, Kamath, Vidyulata, Kumfor, Fiona, Matias-Guiu, Jordi A.|||0000-0001-5520-2708, Narme, Pauline, Nielsen, T. Rune, Okhuevbie, Daniel, Piña-Escudero, Stefanie D., Garcia, Ramiro Ruiz, Scarioni, Marta, Slachevsky, Andrea, Suarez-Gonzalez, Aida, Tee, Boon Lead, Tsoy, Elena, Ulugut, Hülya, Babulal, Ganesh Muneshwar, Onyike, Chiadi U.
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:301685
Acceso en línea:https://ddd.uab.cat/record/301685
https://dx.doi.org/urn:doi:10.1002/alz.13129
Access Level:acceso abierto
Palabra clave:Cultural diversity
Diagnosis
Ethnicity
Frontotemporal dementia
Language
Literacy
Neuropsychological tests
Primary progressive aphasia
Descripción
Sumario:Frontotemporal dementia (FTD) is one of the leading causes of dementia before age 65 and often manifests as abnormal behavior (in behavioral variant FTD) or language impairment (in primary progressive aphasia). FTD's exact clinical presentation varies by culture, language, education, social norms, and other socioeconomic factors; current research and clinical practice, however, is mainly based on studies conducted in North America and Western Europe. Changes in diagnostic criteria and procedures as well as new or adapted cognitive tests are likely needed to take into consideration global diversity. This perspective paper by two professional interest areas of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment examines how increasing global diversity impacts the clinical presentation, screening, assessment, and diagnosis of FTD and its treatment and care. It subsequently provides recommendations to address immediate needs to advance global FTD research and clinical practice.

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