Splice-site variants of the breast cancer susceptibility gene ATM. BRIDGES_Project-2

Folder: 1.Sequences - Sub-folder cDNA. Transcript Sequencing. Sub-folders: - ATM_19-22: 31 *.ab1 files of transcripts generated by variants introduced into minigene mgATM_19-22 - ATM_41-44: 15 *.ab1 files of transcripts generated by variants introduced into minigene mgATM_41-44 - ATM_55-63: 32 *.ab1...

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Detalles Bibliográficos
Autores: Llinares-Burguet, Inés, Velasco, Eladio
Tipo de recurso: conjunto de datos
Fecha de publicación:2025
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/403423
Acceso en línea:http://hdl.handle.net/10261/403423
Access Level:acceso abierto
Palabra clave:Breast cancer
Susceptibility genes
Ataxia-Telangiectasia Mutated Gene
ATM
Variants
Splicing
Aberrant splicing
Minigenes
Descripción
Sumario:Folder: 1.Sequences - Sub-folder cDNA. Transcript Sequencing. Sub-folders: - ATM_19-22: 31 *.ab1 files of transcripts generated by variants introduced into minigene mgATM_19-22 - ATM_41-44: 15 *.ab1 files of transcripts generated by variants introduced into minigene mgATM_41-44 - ATM_55-63: 32 *.ab1 files of transcripts generated by variants introduced into minigene mgATM_55-63 - Sub-folder: Minigenes. Sequence files of wild type and mutant constructs. Sub-folders: - ATM_19-22: 17 *.ab1 files. - ATM_41-44: 11 *.ab1 files. - ATM_55-63: 25 *.ab1 files. • Folder: 2.Fragment_Analysis. Fluorescent Fragment Analysis of splicing assays. Sub-folders: - ATM_19-22: 53 *.fsa files of fluorescent fragment analysis of variant-spicing assays. - ATM_41-44: 30 *.fsa files of fluorescent fragment analysis of variant-spicing assays. - ATM_55-63: 72 *.fsa files of fluorescent fragment analysis of variant-spicing assays.