Management of borderline ovarian tumours: A comprehensive review of the literature

Borderline ovarian tumours differ from epithelial ovarian cancer by their low incidence, frequent association with infertility, low association with mutations in BCRA genes, different percentages of the most common histological types, early stage diagnosis, and high survival rate, even when associat...

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Detalles Bibliográficos
Autores: Abascal-Saiz, Alejandra, Sotillo-Mallo, Laura, De Santiago García, Francisco Javier, Zapardiel Gutiérrez, Ignacio
Tipo de recurso: artículo
Fecha de publicación:2014
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/662474
Acceso en línea:http://hdl.handle.net/10486/662474
https://dx.doi.org/10.3332/ecancer.2014.403
Access Level:acceso abierto
Palabra clave:Borderline ovarian tumour
Fertility-sparing surgery
Management
Medicina
Descripción
Sumario:Borderline ovarian tumours differ from epithelial ovarian cancer by their low incidence, frequent association with infertility, low association with mutations in BCRA genes, different percentages of the most common histological types, early stage diagnosis, and high survival rate, even when associated with peritoneal involvement. They occur in younger women, which is why one of the objectives in these patients will be the preservation of fertility. The management of these tumours has been widely discussed and still continues to be controversial. The latest findings underscore the importance of full staging in both radical and conservative surgery, to choose the most comprehensive treatment and obtain an accurate prognosis. One of the objectives of this article shall be the in-depth review of the indications, benefits, and disadvantages of each type of surgery, as well as the usefulness of the medical treatment. In addition, the article aims to review follow-up guidelines and to clarify the main prognostic factors that affect recurrence and survival of these patients.