Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons

[Background and purpose] Monte Carlo simulations as well as analytical computations of proton transport in material media require accurate values of multiple Coulomb scattering (MCS) angles. High-quality experimental data on MCS angles in the energy range for proton therapy are, however, sparse. In...

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Autores: Verbeek, Nico, Wulff, Jörg, Janson, Martin, Bäumer, Christian, Zahid, Sameera, Timmermann, Beate, Brualla Barberá, Lorenzo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/415066
Acceso en línea:http://hdl.handle.net/10261/415066
https://api.elsevier.com/content/abstract/scopus_id/85104947255
Access Level:acceso abierto
Palabra clave:Geant4
Monte Carlo
PENELOPE
PENH
TOPAS
Multiple scattering
Proton
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
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dc.title.none.fl_str_mv Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons
title Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons
spellingShingle Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons
Verbeek, Nico
Geant4
Monte Carlo
PENELOPE
PENELOPE
PENH
TOPAS
Multiple scattering
Proton
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
title_short Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons
title_full Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons
title_fullStr Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons
title_full_unstemmed Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons
title_sort Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons
dc.creator.none.fl_str_mv Verbeek, Nico
Wulff, Jörg
Janson, Martin
Bäumer, Christian
Zahid, Sameera
Timmermann, Beate
Brualla Barberá, Lorenzo
author Verbeek, Nico
author_facet Verbeek, Nico
Wulff, Jörg
Janson, Martin
Bäumer, Christian
Zahid, Sameera
Timmermann, Beate
Brualla Barberá, Lorenzo
author_role author
author2 Wulff, Jörg
Janson, Martin
Bäumer, Christian
Zahid, Sameera
Timmermann, Beate
Brualla Barberá, Lorenzo
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv European Commission
Brualla, Lorenzo [0000-0003-3385-9623]
dc.subject.none.fl_str_mv Geant4
Monte Carlo
PENELOPE
PENELOPE
PENH
TOPAS
Multiple scattering
Proton
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
topic Geant4
Monte Carlo
PENELOPE
PENELOPE
PENH
TOPAS
Multiple scattering
Proton
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
description [Background and purpose] Monte Carlo simulations as well as analytical computations of proton transport in material media require accurate values of multiple Coulomb scattering (MCS) angles. High-quality experimental data on MCS angles in the energy range for proton therapy are, however, sparse. In this work, MCS modeling in proton transport was evaluated employing an experimental method to measure these angles on a medical proton beamline in clinically relevant materials. Results are compared to Monte Carlo simulations and analytical models.
publishDate 2021
dc.date.none.fl_str_mv 2021
2026
2026
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/415066
https://api.elsevier.com/content/abstract/scopus_id/85104947255
url http://hdl.handle.net/10261/415066
https://api.elsevier.com/content/abstract/scopus_id/85104947255
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
Proyecto financiado HARMONIC (Health effects of cArdiac fluoRoscopy and MOderN radIotherapy in paediatriCs) del programa EURATOM la Comisión Europea (grant agreement number 847707
The underlying dataset has been published as supplementary material of the article in the publisher platform at DOI https://doi.org/10.1002/mp.14860
https://doi.org/10.1002/mp.14860
No
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley-VCH
publisher.none.fl_str_mv Wiley-VCH
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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spelling Experiments and Monte Carlo simulations on multiple Coulomb scattering of protonsVerbeek, NicoWulff, JörgJanson, MartinBäumer, ChristianZahid, SameeraTimmermann, BeateBrualla Barberá, LorenzoGeant4Monte CarloPENELOPEPENELOPEPENHTOPASMultiple scatteringProtonhttp://metadata.un.org/sdg/3Ensure healthy lives and promote well-being for all at all ages[Background and purpose] Monte Carlo simulations as well as analytical computations of proton transport in material media require accurate values of multiple Coulomb scattering (MCS) angles. High-quality experimental data on MCS angles in the energy range for proton therapy are, however, sparse. In this work, MCS modeling in proton transport was evaluated employing an experimental method to measure these angles on a medical proton beamline in clinically relevant materials. Results are compared to Monte Carlo simulations and analytical models.[Materials and methods] Aluminum, brass, and lucite (PMMA) scatterers of clinically relevant thicknesses were irradiated with protons at 100, 160, and 220 MeV. Resulting spatial distributions of individual pencil beams were measured with a scintillating screen. The MCS angles were determined by deconvolution and a virtual point source approach. Results were compared to those obtained with the Monte Carlo codes PENH, TOPAS, and RayStation Monte Carlo, as well as the analytical models RayStation Pencil Beam Algorithm and the Molière/Fano/Hanson variant of the Molière theory.[Results] Experimental data obtained with the presented methodology agree with previously published results within 6%, with an average deviation of 3%. The combined average uncertainty of the experimental data yielded 1.8%, while the combined maximum uncertainty was below 4%. The obtained Monte Carlo results for PENH, TOPAS, and RayStation deviate on average for all considered energies, materials and thicknesses, by 2.5%, 3.4%, and 2.8% from the experimental data, respectively. For the analytical models, the average deviations amount to 4.5% and 2.9% for the RayStation Pencil Beam Algorithm and the Molière/Fano/Hanson model, respectively.[Conclusion] The experimental method developed for the present work allowed to measure MCS angles in clinical proton facilities with good accuracy. The presented method permits to extend the database on experimental MCS angles which is rather limited. This work further provides benchmark data for lucite in thicknesses relevant for clinical applications. The data may serve to validate dose engines of treatment planning systems and secondary dose check software. The Monte Carlo and analytical algorithms studied are capable of reproducing MCS data within the required accuracy for clinical applications.Proyecto financiado HARMONIC (Health effects of cArdiac fluoRoscopy and MOderN radIotherapy in paediatriCs) del programa EURATOM la Comisión Europea (grant agreement number 847707) del cual yo era Investigador Principal y Task Leader.NV, JW, CB, BT, and LB are thankful to the HARMONIC project. The HARMONIC project (Health effects of cArdiac fluoRoscopy and MOderN radIotherapy in paediatriCs) has received funding from the Euratom research and training programme 2014-2018 under grant agreement No 847707. NV, JW, CB, and LB acknowledge support from the Spanish Junta de Andalucia under grant agreement P18-RT-3237.Peer reviewedWiley-VCHEuropean CommissionBrualla, Lorenzo [0000-0003-3385-9623]202620262021info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/415066https://api.elsevier.com/content/abstract/scopus_id/85104947255reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#Proyecto financiado HARMONIC (Health effects of cArdiac fluoRoscopy and MOderN radIotherapy in paediatriCs) del programa EURATOM la Comisión Europea (grant agreement number 847707The underlying dataset has been published as supplementary material of the article in the publisher platform at DOI https://doi.org/10.1002/mp.14860https://doi.org/10.1002/mp.14860Noinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/4150662026-05-22T06:33:51Z
score 15,812429

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