New contact lens materials for presbyopia

The rapid ageing of the global population represents critical challenges to healthcare systems, as age-related physiological changes progressively impair the functions of tissues and organs. Similarly to the other body tissues, ocular tissues exhibit increased oxidative and inflammatory damage as co...

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Detalles Bibliográficos
Autor: Lim, Clara
Tipo de recurso: tesis doctoral
Fecha de publicación:2026
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/133864
Acceso en línea:https://hdl.handle.net/20.500.14352/133864
Access Level:acceso abierto
Palabra clave:617.753.4(043.2)
Presbicia
Presbyopia
Óptica y optometría
2209 Óptica
Descripción
Sumario:The rapid ageing of the global population represents critical challenges to healthcare systems, as age-related physiological changes progressively impair the functions of tissues and organs. Similarly to the other body tissues, ocular tissues exhibit increased oxidative and inflammatory damage as consequence of aging. Damage that compromises the integrity of the eye but also leads to a progressive deterioration of visual function.Among the most common age-related changes is presbyopia. This condition typically develops around the age of 45 and causes a progressive decline in near-focusability. Current presbyopia correction methods rely primarily on eyeglasses, which, despite its effectiveness, cannot compensate for its negative impact on the quality of life. In contrast, contact lenses (CL) provide a wider field of vision and are more aesthetically pleasing than spectacles, making them an attractive alternative particularly suited to modern lifestyles. Nevertheless, their adoption remains limited, mainly due to the discomfort experienced by presbyope wearers. This discomfort can be due to the high basal level of inflammation on the ocular surface of presbyopes triggered by age-induced changes and CL wear. For this reason, it is necessary to develop new materials that minimize the inflammatory response and, thus, the discomfort of presbyopic wearing lenses...