Factores nutricionales y no nutricionales pueden afectar la fertilidad masculina mediante mecanismos epigenéticos
Infertility rate is globally increasing. It is estimated that approximately 15% of couples in reproductive age have troubles conceiving. Half of these couples present with problems related to male infertility or subfertility, alone or in combination with female problems. During the last decade, infe...
| Autores: | , |
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| Tipo de recurso: | artículo |
| Fecha de publicación: | 2016 |
| País: | España |
| Institución: | Universitat Oberta de Catalunya (UOC) |
| Repositorio: | O2, repositorio institucional de la UOC |
| OAI Identifier: | oai:openaccess.uoc.edu:10609/70684 |
| Acceso en línea: | http://hdl.handle.net/10609/70684 |
| Access Level: | acceso abierto |
| Palabra clave: | infertilidad masculina epigenética nutrición infertilitat masculina epigenètica nutrició male infertility epigenetics nutrition Infertility, Male Esterilitat masculina Esterilidad masculina |
| Sumario: | Infertility rate is globally increasing. It is estimated that approximately 15% of couples in reproductive age have troubles conceiving. Half of these couples present with problems related to male infertility or subfertility, alone or in combination with female problems. During the last decade, infertility has been studied from a multifactorial perspective, which includes interactions between different genetics, epigenetics, biochemical and physiological situations of the patients. The present review aims to describe epigenetic mechanisms that can be modulated by nutritional aspects and which are related to the aetiology of male infertility and transgenerational inheritance. Extensive search of scientific publications was performed in specialized electronic databases: NBCI, Elsevier, Scielo, Scirus and Science Direct. Several published works have shown the importance of nutritional status in man's fertility, and more specifically, the ability of diet components to modify the epigenetic profiles, affecting not only their fertility, but also increasing the possibility to be transmitted to the offspring. This mechanism has been called transgenerational inheritance. |
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