New treatments for Prosthetic Infections:Microparticles and personalised 3D printed Implants
Currently, joint replacement surgeries, or arthroplasties, are becoming increasingly common, but they are associated with a high risk of infection, resulting in periprosthetic joint infections (PJIs). These infections are typically caused by bacteria from the patient's skin or the surgical envi...
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| Tipo de recurso: | tesis doctoral |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Universidad Complutense de Madrid (UCM) |
| Repositorio: | Docta Complutense |
| Idioma: | inglés |
| OAI Identifier: | oai:docta.ucm.es:20.500.14352/131073 |
| Acceso en línea: | https://hdl.handle.net/20.500.14352/131073 |
| Access Level: | acceso abierto |
| Palabra clave: | 616.72-089. 8(043.2) Artoplastia Artroplasty Medicina 3314.02 Prótesis |
| Sumario: | Currently, joint replacement surgeries, or arthroplasties, are becoming increasingly common, but they are associated with a high risk of infection, resulting in periprosthetic joint infections (PJIs). These infections are typically caused by bacteria from the patient's skin or the surgical environment, which can adhere to the prosthetic components and form a microbial community called biofilm. This can trigger infections that result in pain, loss of mobility, and even death, translating into a significant economic burden for healthcare systems. The most used solution involves a new surgery to remove the infected prosthesis, replacing it temporarily with antibiotic-loaded bone cement for several weeks, followed by a second procedure to implant a new prosthesis... |
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