Reassessing the status of antiphospholipid syndrome in systemic lupus erythematosus.

The antiphospholipid syndrome was initially described in 1986. To reassess the validity of antiphospholipid antibodies in systemic lupus erythematosus (SLE), 95 patients with SLE were studied. Their antiphospholipid antibody profile was analysed and correlated with clinical findings such as thrombos...

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Detalles Bibliográficos
Autores: Vianna, Joao L., Haga, Hans J., Tripathi, Poonam, Cervera i Segura, Ricard, 1960-, Khamashta, Munther A., Hughes, Graham R. V. (Graham Robert Vivian)
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1992
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/22431
Acceso en línea:https://hdl.handle.net/2445/22431
Access Level:acceso abierto
Palabra clave:Lupus eritematós
Síndrome antifosfolipídica
Estudi de casos
Lupus erythematosus
Antiphospholipid syndrome
Case studies
Descripción
Sumario:The antiphospholipid syndrome was initially described in 1986. To reassess the validity of antiphospholipid antibodies in systemic lupus erythematosus (SLE), 95 patients with SLE were studied. Their antiphospholipid antibody profile was analysed and correlated with clinical findings such as thrombosis, abortions, or thrombocytopenia. A low prevalence of these antibodies was found (13 patients; 14%) with a high specificity for thrombosis (92%) and abortions (92%). The importance of anticardiolipin antibodies as a risk factor for thrombosis or abortions, or both, in patients with SLE is reaffirmed by this work.