Bone marrox regeneration afrer hormonal therapy in patients with bone metastases from prostate carcinoma

Two patients with prostate carcinoma and bone metastases were treated with hormonal therapy. Radioimmune imaging of bone marrow performed with 99mTc-labeled antigranulocyte antibody BW 250/183 before treatment demonstrated absence of granulopoietic bone marrow in extensive regions of the central and...

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Detalhes bibliográficos
Autores: Berná, Lluis, Germá, Josep R., Estorach, Montserrat, Torres, Gustavo, Blanco, Remei, Carrió, Ignasi
Formato: artículo
Estado:Versión publicada
Fecha de publicación:1991
País:España
Recursos:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/177302
Acesso em linha:https://hdl.handle.net/2445/177302
Access Level:acceso abierto
Palavra-chave:Anticossos monoclonals
Medul·la òssia
Càncer d'ossos
Càncer de pròstata
Monoclonal antibodies
Bone marrow
Bones cancer
Prostate cancer
Descrição
Resumo:Two patients with prostate carcinoma and bone metastases were treated with hormonal therapy. Radioimmune imaging of bone marrow performed with 99mTc-labeled antigranulocyte antibody BW 250/183 before treatment demonstrated absence of granulopoietic bone marrow in extensive regions of the central and proximal peripheral skeleton, indicating diffuse bone marrow invasion. Bone marrow scans performed after treatment demonstrated presence of granulopoietic bone marrow in these regions, indicating bone marrow regeneration. This finding was consistent with favorable response to treatment.