Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extracts

5 pages, 1 table.

Detalles Bibliográficos
Autores: Lizárraga, Daneida, Lozano, Carles, Touriño, Sonia, Centelles, Josep J., Torres, Josep Lluís, Cascante, Marta
Tipo de recurso: artículo
Fecha de publicación:2008
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/28650
Acceso en línea:http://hdl.handle.net/10261/28650
Access Level:acceso abierto
Palabra clave:Polimerization
Galloylation
Antiproliferative properties
Procyanidin-rich
id ES_35339be59593e4e9c7653ff1228b1817
oai_identifier_str oai:digital.csic.es:10261/28650
network_acronym_str ES
network_name_str España
repository_id_str
spelling Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extractsLizárraga, DaneidaLozano, CarlesTouriño, SoniaCentelles, Josep J.Torres, Josep LluísCascante, MartaPolimerizationGalloylationAntiproliferative propertiesProcyanidin-rich5 pages, 1 table.Natural polyphenolic compounds from plants and fruits have been reported to be potent antioxidants and to present antitumoral properties. The difficulty to clearly identify structure/antitumoral activity of this family of compounds makes difficult to optimize the formulation of combinations of polyphenolic extracts from different plants or fruits to achieve the best antitumoral potency. Recent advances have been achieved in this field from the exhaustive characterization of polyphenolic extracts with different degree of polymerization and percentage of galloylation. Here we review the results obtained in this field from our team (Lizarraga et al., 2007; Lozano et al., 2006; Lozano et al., 2005; Matito et al., 2003; Tourino et al., 2008; Tourino et al., 2005) that relate degree of polymerization and galloylation to radical scavenging capacity, tumor cell proliferation inhibition and induction of apoptosis. From this review we concluded that natural polyphenolic extract with high degree of polymerization and galloylation will present the higher antiproliferative and induction of apoptosis capacities.This work was supported by Spanish Government and the European Union FEDER funds (SAF2005-01627 and AGL2004-07579-C04-03/ALI) and ISCIII-RTICC (RD06/0020/0046); Generalitat de Catalunya (2005SGR00204; 2006ITT-10007).Peer reviewedUniversidad de Vigo201020102008info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501http://hdl.handle.net/10261/28650reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttp://ejeafche.uvigo.es/component/option,com_docman/task,doc_view/gid,407/Itemid,33info:eu-repo/semantics/openAccessoai:digital.csic.es:10261/286502026-05-22T06:33:51Z
dc.title.none.fl_str_mv Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extracts
title Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extracts
spellingShingle Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extracts
Lizárraga, Daneida
Polimerization
Galloylation
Antiproliferative properties
Procyanidin-rich
title_short Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extracts
title_full Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extracts
title_fullStr Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extracts
title_full_unstemmed Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extracts
title_sort Polymerization and galloylation: two important aspects for antiproliferative properties of procyanidin-rich natural extracts
dc.creator.none.fl_str_mv Lizárraga, Daneida
Lozano, Carles
Touriño, Sonia
Centelles, Josep J.
Torres, Josep Lluís
Cascante, Marta
author Lizárraga, Daneida
author_facet Lizárraga, Daneida
Lozano, Carles
Touriño, Sonia
Centelles, Josep J.
Torres, Josep Lluís
Cascante, Marta
author_role author
author2 Lozano, Carles
Touriño, Sonia
Centelles, Josep J.
Torres, Josep Lluís
Cascante, Marta
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Polimerization
Galloylation
Antiproliferative properties
Procyanidin-rich
topic Polimerization
Galloylation
Antiproliferative properties
Procyanidin-rich
description 5 pages, 1 table.
publishDate 2008
dc.date.none.fl_str_mv 2008
2010
2010
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/28650
url http://hdl.handle.net/10261/28650
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv http://ejeafche.uvigo.es/component/option,com_docman/task,doc_view/gid,407/Itemid,33
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidad de Vigo
publisher.none.fl_str_mv Universidad de Vigo
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869405866679074816
score 15,811543

Similares en LA Referencia