Update on Asthma–COPD Overlap (ACO): A Narrative Review

MPOC; Asma; Pronòstic

Detalles Bibliográficos
Autores: Mekov, Evgeni, Nuñez Dubon, Alexa Gabriela, Sin, Don D, Ichinose, Masakazu, Maselli, Diego Jose, Miravitlles Fernández, Marc, Rhee, Chin Kook
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Departament de Salut de la Generalitat de Catalunya (DS)
Repositorio:Scientia. Dipòsit d'Informació Digital del Departament de Salut
OAI Identifier:oai:scientiasalut.gencat.cat:11351/7234
Acceso en línea:https://hdl.handle.net/11351/7234
Access Level:acceso abierto
Palabra clave:Asma - Prognosi
Pulmons - Malalties obstructives - Prognosi
Corticosteroides - Ús terapèutic
DISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic Obstructive
DISEASES::Respiratory Tract Diseases::Bronchial Diseases::Asthma
CHEMICALS AND DRUGS::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex Hormones
Other subheadings::Other subheadings::/therapeutic use
ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónica
ENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::asma
COMPUESTOS QUÍMICOS Y DROGAS::hormonas, sustitutos de hormonas y antagonistas de hormonas::hormonas::hormonas de la corteza suprarrenal
Otros calificadores::Otros calificadores::/uso terapéutico
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network_name_str España
repository_id_str
spelling Update on Asthma–COPD Overlap (ACO): A Narrative ReviewMekov, EvgeniNuñez Dubon, Alexa GabrielaSin, Don DIchinose, MasakazuMaselli, Diego JoseMiravitlles Fernández, MarcRhee, Chin KookAsma - PrognosiPulmons - Malalties obstructives - PrognosiCorticosteroides - Ús terapèuticDISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic ObstructiveDISEASES::Respiratory Tract Diseases::Bronchial Diseases::AsthmaCHEMICALS AND DRUGS::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex HormonesOther subheadings::Other subheadings::/therapeutic useENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónicaENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::asmaCOMPUESTOS QUÍMICOS Y DROGAS::hormonas, sustitutos de hormonas y antagonistas de hormonas::hormonas::hormonas de la corteza suprarrenalOtros calificadores::Otros calificadores::/uso terapéuticoMPOC; Asma; PronòsticEPOC; Asma; PronósticoCOPD; Asthma; PrognosisAlthough chronic obstructive pulmonary disease (COPD) and asthma are well-characterized diseases, they can coexist in a given patient. The term asthma–COPD overlap (ACO) was introduced to describe patients that have clinical features of both diseases and may represent around 25% of COPD patients and around 20% of asthma patients. Despite the increasing interest in ACO, there are still substantial controversies regarding its definition and its position within clinical guidelines for patients with obstructive lung disease. In general, most definitions indicate that ACO patients must present with non-reversible airflow limitation, significant exposure to smoking or other noxious particles or gases, together with features of asthma. In patients with a primary diagnosis of COPD, the identification of ACO has therapeutic implication because the asthmatic component should be treated with inhaled corticosteroids and some studies suggest that the most severe patients may respond to biological agents indicated for severe asthma. This manuscript aims to summarize the current state-of-the-art of ACO. The definitions, prevalence, and clinical manifestations will be reviewed and some innovative aspects, such as genetics, epigenetics, and biomarkers will be addressed. Lastly, the management and prognosis will be outlined as well as the position of ACO in the COPD and asthma guidelines.Dove Medical PressInstitut Català de la Salut[Mekov E] Department of Occupational Diseases, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria. [Nuñez A, Miravitlles M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Spain. [Sin DD] Centre for Heart Lung Innovation, St. Paul’s Hospital, Department of Medicine (Respiratory Division), University of British Columbia, Vancouver, BC, Canada. [Ichinose M] Academic Center of Osaki Citizen Hospital, Miyagi, Japan. [Rhee CK] Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. [Maselli DJ] Division of Pulmonary Diseases & Critical Care, University of Texas Health, South Texas Veterans Health Care System, San Antonio, TX, USAVall d'Hebron Barcelona Hospital Campus202220222021info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/11351/7234Scientiareponame:Scientia. Dipòsit d'Informació Digital del Departament de Salutinstname:Departament de Salut de la Generalitat de Catalunya (DS)InglésInternational Journal of Chronic Obstructive Pulmonary Disease;16https://doi.org/10.2147/COPD.S312560Attribution-NonCommercial 4.0 Internationalhttp://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:scientiasalut.gencat.cat:11351/72342026-06-12T09:38:37Z
dc.title.none.fl_str_mv Update on Asthma–COPD Overlap (ACO): A Narrative Review
title Update on Asthma–COPD Overlap (ACO): A Narrative Review
spellingShingle Update on Asthma–COPD Overlap (ACO): A Narrative Review
Mekov, Evgeni
Asma - Prognosi
Pulmons - Malalties obstructives - Prognosi
Corticosteroides - Ús terapèutic
DISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic Obstructive
DISEASES::Respiratory Tract Diseases::Bronchial Diseases::Asthma
CHEMICALS AND DRUGS::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex Hormones
Other subheadings::Other subheadings::/therapeutic use
ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónica
ENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::asma
COMPUESTOS QUÍMICOS Y DROGAS::hormonas, sustitutos de hormonas y antagonistas de hormonas::hormonas::hormonas de la corteza suprarrenal
Otros calificadores::Otros calificadores::/uso terapéutico
title_short Update on Asthma–COPD Overlap (ACO): A Narrative Review
title_full Update on Asthma–COPD Overlap (ACO): A Narrative Review
title_fullStr Update on Asthma–COPD Overlap (ACO): A Narrative Review
title_full_unstemmed Update on Asthma–COPD Overlap (ACO): A Narrative Review
title_sort Update on Asthma–COPD Overlap (ACO): A Narrative Review
dc.creator.none.fl_str_mv Mekov, Evgeni
Nuñez Dubon, Alexa Gabriela
Sin, Don D
Ichinose, Masakazu
Maselli, Diego Jose
Miravitlles Fernández, Marc
Rhee, Chin Kook
author Mekov, Evgeni
author_facet Mekov, Evgeni
Nuñez Dubon, Alexa Gabriela
Sin, Don D
Ichinose, Masakazu
Maselli, Diego Jose
Miravitlles Fernández, Marc
Rhee, Chin Kook
author_role author
author2 Nuñez Dubon, Alexa Gabriela
Sin, Don D
Ichinose, Masakazu
Maselli, Diego Jose
Miravitlles Fernández, Marc
Rhee, Chin Kook
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Institut Català de la Salut
[Mekov E] Department of Occupational Diseases, Medical Faculty, Medical University of Sofia, Sofia, Bulgaria. [Nuñez A, Miravitlles M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Spain. [Sin DD] Centre for Heart Lung Innovation, St. Paul’s Hospital, Department of Medicine (Respiratory Division), University of British Columbia, Vancouver, BC, Canada. [Ichinose M] Academic Center of Osaki Citizen Hospital, Miyagi, Japan. [Rhee CK] Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. [Maselli DJ] Division of Pulmonary Diseases & Critical Care, University of Texas Health, South Texas Veterans Health Care System, San Antonio, TX, USA
Vall d'Hebron Barcelona Hospital Campus
dc.subject.none.fl_str_mv Asma - Prognosi
Pulmons - Malalties obstructives - Prognosi
Corticosteroides - Ús terapèutic
DISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic Obstructive
DISEASES::Respiratory Tract Diseases::Bronchial Diseases::Asthma
CHEMICALS AND DRUGS::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex Hormones
Other subheadings::Other subheadings::/therapeutic use
ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónica
ENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::asma
COMPUESTOS QUÍMICOS Y DROGAS::hormonas, sustitutos de hormonas y antagonistas de hormonas::hormonas::hormonas de la corteza suprarrenal
Otros calificadores::Otros calificadores::/uso terapéutico
topic Asma - Prognosi
Pulmons - Malalties obstructives - Prognosi
Corticosteroides - Ús terapèutic
DISEASES::Respiratory Tract Diseases::Lung Diseases::Lung Diseases, Obstructive::Pulmonary Disease, Chronic Obstructive
DISEASES::Respiratory Tract Diseases::Bronchial Diseases::Asthma
CHEMICALS AND DRUGS::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Adrenal Cortex Hormones
Other subheadings::Other subheadings::/therapeutic use
ENFERMEDADES::enfermedades respiratorias::enfermedades pulmonares::enfermedades pulmonares obstructivas::enfermedad pulmonar obstructiva crónica
ENFERMEDADES::enfermedades respiratorias::enfermedades bronquiales::asma
COMPUESTOS QUÍMICOS Y DROGAS::hormonas, sustitutos de hormonas y antagonistas de hormonas::hormonas::hormonas de la corteza suprarrenal
Otros calificadores::Otros calificadores::/uso terapéutico
description MPOC; Asma; Pronòstic
publishDate 2021
dc.date.none.fl_str_mv 2021
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11351/7234
url https://hdl.handle.net/11351/7234
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv International Journal of Chronic Obstructive Pulmonary Disease;16
https://doi.org/10.2147/COPD.S312560
dc.rights.none.fl_str_mv Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial 4.0 International
http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Dove Medical Press
publisher.none.fl_str_mv Dove Medical Press
dc.source.none.fl_str_mv Scientia
reponame:Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname:Departament de Salut de la Generalitat de Catalunya (DS)
instname_str Departament de Salut de la Generalitat de Catalunya (DS)
reponame_str Scientia. Dipòsit d'Informació Digital del Departament de Salut
collection Scientia. Dipòsit d'Informació Digital del Departament de Salut
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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