Identification and characterization of human observational studies in nutritional epidemiology on gut microbiomics for joint data analysis

In any research field, data access and data integration are major challenges that even large, well-established consortia face. Although data sharing initiatives are increasing, joint data analyses on nutrition and microbiomics in health and disease are still scarce. We aimed to identify observationa...

Descripción completa

Detalles Bibliográficos
Autores: Pinart, Mariona, Nimptsch, Katharina, Forslund, Sofía K., Schlicht, Kristina, Gueimonde Fernández, Miguel, Brigidi, Patrizia, Turroni, Silvia, Ahrens, Wolfgang, Hebestreit, Antje, Wolters, Maike, Dötsch, Andreas, Nöthlings, Ute, Oluwagbemigun, Kolade, Cuadrat, Rafael R.C., Schulze, Matthias B., Standl, Marie, Schloter, Michael, Angelis, Maria de, Iozzo, Patricia, Guzzardi, Maria Angela, Vlaemynck, Geertrui, Penders, John, Jonkers, Daisy M. A. E., Stemmer, Maya, Chiesa, Giulia, Cavalieri, Duccio, Filippo, Carlotta de, Ercolini, Danilo, Filippis, Francesca de, Ribet, David, Achamrah, Najate, Tavolacci, Marie-Pierre, Déchelotte, Pierre, Bouwman, Jildau, Laudes, Matthias, Pischon, Tobias
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/263555
Acceso en línea:http://hdl.handle.net/10261/263555
Access Level:acceso abierto
Palabra clave:Microbiome
Dietary intake
Metadata
Data integration
Data sharing
Observational studies
Metabolome
Descripción
Sumario:In any research field, data access and data integration are major challenges that even large, well-established consortia face. Although data sharing initiatives are increasing, joint data analyses on nutrition and microbiomics in health and disease are still scarce. We aimed to identify observational studies with data on nutrition and gut microbiome composition from the Intestinal Microbiomics (INTIMIC) Knowledge Platform following the findable, accessible, interoperable, and reusable (FAIR) principles. An adapted template from the European Nutritional Phenotype Assessment and Data Sharing Initiative (ENPADASI) consortium was used to collect microbiome-specific information and other related factors. In total, 23 studies (17 longitudinal and 6 cross-sectional) were identified from Italy (7), Germany (6), Netherlands (3), Spain (2), Belgium (1), and France (1) or multiple countries (3). Of these, 21 studies collected information on both dietary intake (24 h dietary recall, food frequency questionnaire (FFQ), or Food Records) and gut microbiome. All studies collected stool samples. The most often used sequencing platform was Illumina MiSeq, and the preferred hypervariable regions of the 16S rRNA gene were V3–V4 or V4. The combination of datasets will allow for sufficiently powered investigations to increase the knowledge and understanding of the relationship between food and gut microbiome in health and disease.

Similares en LA Referencia