In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASIC

[EN] In recent years high efforts have been devoted to enhance spatial and temporal resolutions of PET detectors. However, accurately combining these two main features is, in most of the cases, challenging. Typically, a compromise has to be made between the number of readout channels, scintillator t...

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Authors: Lamprou, Efthymios, F Sánchez, Benlloch Baviera, Jose María|||0000-0001-6073-1436, González Martínez, Antonio Javier
Format: article
Publication Date:2020
Country:España
Institution:Universitat Politècnica de València (UPV)
Repository:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Language:English
OAI Identifier:oai:riunet.upv.es:10251/162256
Online Access:https://riunet.upv.es/handle/10251/162256
Access Level:Open access
Keyword:TOF-PET
ASIC
Time walk
Crystal arrays
SiPM
Timing resolution
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spelling In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASICLamprou, EfthymiosF SánchezBenlloch Baviera, Jose María|||0000-0001-6073-1436González Martínez, Antonio JavierTOF-PETASICTime walkCrystal arraysSiPMTiming resolution[EN] In recent years high efforts have been devoted to enhance spatial and temporal resolutions of PET detectors. However, accurately combining these two main features is, in most of the cases, challenging. Typically, a compromise has to be made between the number of readout channels, scintillator type and size, and photosensors arrangement if aiming for a good system performance, while keeping a moderate cost. In this work, we have studied several detector configurations for PET based on a set of 8x8 Silicon Photomultiplier (SiPMs) of 3x3 mm(2) active area, and LYSO crystal arrays with different pixel sizes. An exhaustive evaluation in terms of spatial, energy and timing resolution was made for all detector configurations. In some cases, when using pixel sizes different than SiPM active area, a significant amount of scintillation light may spread among several SiPMs. Therefore, we made use of a calibration method considering the different SiPM timing contributions. Best Detector Time Resolution (DTR) of 156 ps FWHM was measured when using 3x3 mm(2) crystal pixels directly coupled to the 3x3 mm(2) SiPMs. However, when using 1.5 mm crystal pixels with the same photosensor array, although we could clearly resolve all crystal pixels, an average DTR of 250 ps FWHM was achieved. We also shed light in this work on the timing dependency of the crystal pixel and photosensor alignment.This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (grant agreement No. 695536) and by the Spanish Ministerio de Economia, Industria y Competitividad under Grant TEC2016-79884-C2-1-R. The first author has also been supported by Generalitat Valenciana, Spain under grant agreement GRISOLIAP-2018-026.ElsevierInstituto de Instrumentación para Imagen MolecularEuropean CommissionGeneralitat ValencianaMinisterio de Economía y CompetitividadRepositorio Institucional de la Universitat Politècnica de València Riunet20202020-10-11journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://riunet.upv.es/handle/10251/162256reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengMinisterio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 TEC2016-79884-C2-1-R DESARROLLO DEL HARDWARE PARA SISTEMA DE DIAGNOSTICO POR IMAGEN MOLECULAR PARA CORAZON EN CONDICIONES DE ESTRESEuropean Commission https://doi.org/10.13039/501100000780 H2020 695536 Innovative PET scanner for dynamic imagingGeneralitat Valenciana https://doi.org/10.13039/501100003359 GRISOLIAP%2F2018%2F026open accesshttp://purl.org/coar/access_right/c_abf2Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/1622562026-06-13T07:49:27Z
dc.title.none.fl_str_mv In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASIC
title In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASIC
spellingShingle In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASIC
Lamprou, Efthymios
TOF-PET
ASIC
Time walk
Crystal arrays
SiPM
Timing resolution
title_short In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASIC
title_full In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASIC
title_fullStr In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASIC
title_full_unstemmed In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASIC
title_sort In-depth evaluation of TOF-PET detectors based on crystal arrays and the TOFPET2 ASIC
dc.creator.none.fl_str_mv Lamprou, Efthymios
F Sánchez
Benlloch Baviera, Jose María|||0000-0001-6073-1436
González Martínez, Antonio Javier
author Lamprou, Efthymios
author_facet Lamprou, Efthymios
F Sánchez
Benlloch Baviera, Jose María|||0000-0001-6073-1436
González Martínez, Antonio Javier
author_role author
author2 F Sánchez
Benlloch Baviera, Jose María|||0000-0001-6073-1436
González Martínez, Antonio Javier
author2_role author
author
author
dc.contributor.none.fl_str_mv Instituto de Instrumentación para Imagen Molecular
European Commission
Generalitat Valenciana
Ministerio de Economía y Competitividad
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv TOF-PET
ASIC
Time walk
Crystal arrays
SiPM
Timing resolution
topic TOF-PET
ASIC
Time walk
Crystal arrays
SiPM
Timing resolution
description [EN] In recent years high efforts have been devoted to enhance spatial and temporal resolutions of PET detectors. However, accurately combining these two main features is, in most of the cases, challenging. Typically, a compromise has to be made between the number of readout channels, scintillator type and size, and photosensors arrangement if aiming for a good system performance, while keeping a moderate cost. In this work, we have studied several detector configurations for PET based on a set of 8x8 Silicon Photomultiplier (SiPMs) of 3x3 mm(2) active area, and LYSO crystal arrays with different pixel sizes. An exhaustive evaluation in terms of spatial, energy and timing resolution was made for all detector configurations. In some cases, when using pixel sizes different than SiPM active area, a significant amount of scintillation light may spread among several SiPMs. Therefore, we made use of a calibration method considering the different SiPM timing contributions. Best Detector Time Resolution (DTR) of 156 ps FWHM was measured when using 3x3 mm(2) crystal pixels directly coupled to the 3x3 mm(2) SiPMs. However, when using 1.5 mm crystal pixels with the same photosensor array, although we could clearly resolve all crystal pixels, an average DTR of 250 ps FWHM was achieved. We also shed light in this work on the timing dependency of the crystal pixel and photosensor alignment.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-10-11
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/162256
url https://riunet.upv.es/handle/10251/162256
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Ministerio de Economía y Competitividad http://dx.doi.org/10.13039/501100003329 TEC2016-79884-C2-1-R DESARROLLO DEL HARDWARE PARA SISTEMA DE DIAGNOSTICO POR IMAGEN MOLECULAR PARA CORAZON EN CONDICIONES DE ESTRES
European Commission https://doi.org/10.13039/501100000780 H2020 695536 Innovative PET scanner for dynamic imaging
Generalitat Valenciana https://doi.org/10.13039/501100003359 GRISOLIAP%2F2018%2F026
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento - No comercial - Sin obra derivada (by-nc-nd)
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento - No comercial - Sin obra derivada (by-nc-nd)
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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