Diabetic Retinopathy and Ocular Melanoma: How far we are?

Diabetic retinopathy causes vascular damage to retinal neurons, presenting characteristics of chronic inflammation. The development of new therapies capable of combating vision loss involves knowledge of inflammatory retinal changes. Studies in animal models and patients with diabetes have shown a h...

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Autores: Souto, Eliana B., Campos, Joana R., Da Ana, Raquel, Fangueiro, Joana F., Martins-Gomes, Carlos, Durazzo, Alessandra, Lucarini, Massimo, Sánchez-López, E. (Elena), Espina García, Marta, García López, María Luisa, Silva, Amélia M., Mendonça, Fernando, Santini, Antonello, Souto, Selma B.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/166560
Acceso en línea:https://hdl.handle.net/2445/166560
Access Level:acceso abierto
Palabra clave:Angiogènesi
Factor de creixement de l'endoteli vascular
Retinopatia diabètica
Melanoma
Ceguesa
Neovascularization
Vascular endothelial growth factors
Diabetic retinopathy
Blindness
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repository_id_str
spelling Diabetic Retinopathy and Ocular Melanoma: How far we are?Souto, Eliana B.Campos, Joana R.Da Ana, RaquelFangueiro, Joana F.Martins-Gomes, CarlosDurazzo, AlessandraLucarini, MassimoSánchez-López, E. (Elena)Espina García, MartaGarcía López, María LuisaSilva, Amélia M.Mendonça, FernandoSantini, AntonelloSouto, Selma B.AngiogènesiFactor de creixement de l'endoteli vascularRetinopatia diabèticaMelanomaCeguesaNeovascularizationVascular endothelial growth factorsDiabetic retinopathyMelanomaBlindnessDiabetic retinopathy causes vascular damage to retinal neurons, presenting characteristics of chronic inflammation. The development of new therapies capable of combating vision loss involves knowledge of inflammatory retinal changes. Studies in animal models and patients with diabetes have shown a high expression of the inflammatory molecules that are involved in the progression of diabetic retinopathy. Uveal melanoma is an eye tumour that remains highly deadly, because despite the correct treatment, it still causes metastasis in about 50% of patients. This type of tumour has the ability to produce and store melanin, which may result in resistance to therapy. Over time there has been development of new therapies for this disease, such as radiotherapy and surgical resection. In this review, we discuss diabetic retinopathy and ocular melanoma, their relationship with angiogenesis and the current anti-angiogenic therapies for their treatmentMDPI2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/166560Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.3390/app10082777Applied Sciences, 2020, vol. 10, p. 2777-https://doi.org/10.3390/app10082777cc-by (c) Souto, Eliana B. et al., 2020http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1665602026-05-27T06:46:51Z
dc.title.none.fl_str_mv Diabetic Retinopathy and Ocular Melanoma: How far we are?
title Diabetic Retinopathy and Ocular Melanoma: How far we are?
spellingShingle Diabetic Retinopathy and Ocular Melanoma: How far we are?
Souto, Eliana B.
Angiogènesi
Factor de creixement de l'endoteli vascular
Retinopatia diabètica
Melanoma
Ceguesa
Neovascularization
Vascular endothelial growth factors
Diabetic retinopathy
Melanoma
Blindness
title_short Diabetic Retinopathy and Ocular Melanoma: How far we are?
title_full Diabetic Retinopathy and Ocular Melanoma: How far we are?
title_fullStr Diabetic Retinopathy and Ocular Melanoma: How far we are?
title_full_unstemmed Diabetic Retinopathy and Ocular Melanoma: How far we are?
title_sort Diabetic Retinopathy and Ocular Melanoma: How far we are?
dc.creator.none.fl_str_mv Souto, Eliana B.
Campos, Joana R.
Da Ana, Raquel
Fangueiro, Joana F.
Martins-Gomes, Carlos
Durazzo, Alessandra
Lucarini, Massimo
Sánchez-López, E. (Elena)
Espina García, Marta
García López, María Luisa
Silva, Amélia M.
Mendonça, Fernando
Santini, Antonello
Souto, Selma B.
author Souto, Eliana B.
author_facet Souto, Eliana B.
Campos, Joana R.
Da Ana, Raquel
Fangueiro, Joana F.
Martins-Gomes, Carlos
Durazzo, Alessandra
Lucarini, Massimo
Sánchez-López, E. (Elena)
Espina García, Marta
García López, María Luisa
Silva, Amélia M.
Mendonça, Fernando
Santini, Antonello
Souto, Selma B.
author_role author
author2 Campos, Joana R.
Da Ana, Raquel
Fangueiro, Joana F.
Martins-Gomes, Carlos
Durazzo, Alessandra
Lucarini, Massimo
Sánchez-López, E. (Elena)
Espina García, Marta
García López, María Luisa
Silva, Amélia M.
Mendonça, Fernando
Santini, Antonello
Souto, Selma B.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Angiogènesi
Factor de creixement de l'endoteli vascular
Retinopatia diabètica
Melanoma
Ceguesa
Neovascularization
Vascular endothelial growth factors
Diabetic retinopathy
Melanoma
Blindness
topic Angiogènesi
Factor de creixement de l'endoteli vascular
Retinopatia diabètica
Melanoma
Ceguesa
Neovascularization
Vascular endothelial growth factors
Diabetic retinopathy
Melanoma
Blindness
description Diabetic retinopathy causes vascular damage to retinal neurons, presenting characteristics of chronic inflammation. The development of new therapies capable of combating vision loss involves knowledge of inflammatory retinal changes. Studies in animal models and patients with diabetes have shown a high expression of the inflammatory molecules that are involved in the progression of diabetic retinopathy. Uveal melanoma is an eye tumour that remains highly deadly, because despite the correct treatment, it still causes metastasis in about 50% of patients. This type of tumour has the ability to produce and store melanin, which may result in resistance to therapy. Over time there has been development of new therapies for this disease, such as radiotherapy and surgical resection. In this review, we discuss diabetic retinopathy and ocular melanoma, their relationship with angiogenesis and the current anti-angiogenic therapies for their treatment
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/166560
url https://hdl.handle.net/2445/166560
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/app10082777
Applied Sciences, 2020, vol. 10, p. 2777-
https://doi.org/10.3390/app10082777
dc.rights.none.fl_str_mv cc-by (c) Souto, Eliana B. et al., 2020
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Souto, Eliana B. et al., 2020
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301603

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