Quantifying forces in cell biology

Cells exert, sense, and respond to physical forces through an astounding diversity of mechanisms. Here we review recently developed tools to quantify the forces generated by cells. We first review technologies based on sensors of known or assumed mechanical properties, and discuss their applicabilit...

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Detalhes bibliográficos
Autores: Roca-Cusachs Soulere, Pere, Conte, Vito, Trepat Guixer, Xavier
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2017
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/180611
Acesso em linha:https://hdl.handle.net/2445/180611
Access Level:acceso abierto
Palavra-chave:Cèl·lules
Citosquelet
Membranes cel·lulars
Propietats mecàniques
Cells
Cytoskeleton
Cell membranes
Mechanical properties
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spelling Quantifying forces in cell biologyRoca-Cusachs Soulere, PereConte, VitoTrepat Guixer, XavierCèl·lulesCitosqueletMembranes cel·lularsPropietats mecàniquesCellsCytoskeletonCell membranesMechanical propertiesCells exert, sense, and respond to physical forces through an astounding diversity of mechanisms. Here we review recently developed tools to quantify the forces generated by cells. We first review technologies based on sensors of known or assumed mechanical properties, and discuss their applicability and limitations. We then proceed to draw an analogy between these human-made sensors and force sensing in the cell. As mechanics is increasingly revealed to play a fundamental role in cell function we envisage that tools to quantify physical forces may soon become widely applied in life-sciences laboratories.Nature Publishing Group2021202120172021info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion21 p.application/pdfhttps://hdl.handle.net/2445/180611Articles publicats en revistes (Biomedicina)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1038/ncb3564Nature Cell Biology, 2017, vol. 19, num. 7, p. 742-751https://doi.org/10.1038/ncb3564info:eu-repo/grantAgreement/EC/H2020/731957(c) Roca-Cusachs Soulere, Pere et al., 2017info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1806112026-05-29T05:05:01Z
dc.title.none.fl_str_mv Quantifying forces in cell biology
title Quantifying forces in cell biology
spellingShingle Quantifying forces in cell biology
Roca-Cusachs Soulere, Pere
Cèl·lules
Citosquelet
Membranes cel·lulars
Propietats mecàniques
Cells
Cytoskeleton
Cell membranes
Mechanical properties
title_short Quantifying forces in cell biology
title_full Quantifying forces in cell biology
title_fullStr Quantifying forces in cell biology
title_full_unstemmed Quantifying forces in cell biology
title_sort Quantifying forces in cell biology
dc.creator.none.fl_str_mv Roca-Cusachs Soulere, Pere
Conte, Vito
Trepat Guixer, Xavier
author Roca-Cusachs Soulere, Pere
author_facet Roca-Cusachs Soulere, Pere
Conte, Vito
Trepat Guixer, Xavier
author_role author
author2 Conte, Vito
Trepat Guixer, Xavier
author2_role author
author
dc.subject.none.fl_str_mv Cèl·lules
Citosquelet
Membranes cel·lulars
Propietats mecàniques
Cells
Cytoskeleton
Cell membranes
Mechanical properties
topic Cèl·lules
Citosquelet
Membranes cel·lulars
Propietats mecàniques
Cells
Cytoskeleton
Cell membranes
Mechanical properties
description Cells exert, sense, and respond to physical forces through an astounding diversity of mechanisms. Here we review recently developed tools to quantify the forces generated by cells. We first review technologies based on sensors of known or assumed mechanical properties, and discuss their applicability and limitations. We then proceed to draw an analogy between these human-made sensors and force sensing in the cell. As mechanics is increasingly revealed to play a fundamental role in cell function we envisage that tools to quantify physical forces may soon become widely applied in life-sciences laboratories.
publishDate 2017
dc.date.none.fl_str_mv 2017
2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/180611
url https://hdl.handle.net/2445/180611
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1038/ncb3564
Nature Cell Biology, 2017, vol. 19, num. 7, p. 742-751
https://doi.org/10.1038/ncb3564
info:eu-repo/grantAgreement/EC/H2020/731957
dc.rights.none.fl_str_mv (c) Roca-Cusachs Soulere, Pere et al., 2017
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Roca-Cusachs Soulere, Pere et al., 2017
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 21 p.
application/pdf
dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
dc.source.none.fl_str_mv Articles publicats en revistes (Biomedicina)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.81155

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