Spatial dynamics of synthetic microbial mutualists and their parasites
A major force contributing to the emergence of novelty in nature is the presence of cooperative interactions, where two or more components of a system act in synergy, sometimes leading to higher-order, emergent phenomena. Within molecular evolution, the so called hypercycle defines the simplest mode...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2017 |
| País: | España |
| Institución: | Universitat Pompeu Fabra |
| Repositorio: | Repositorio Digital de la UPF |
| OAI Identifier: | oai:repositori.upf.edu:10230/33733 |
| Acceso en línea: | http://hdl.handle.net/10230/33733 http://dx.doi.org/10.1371/journal.pcbi.1005689 |
| Access Level: | acceso abierto |
| Palabra clave: | Microbial ecology Microbial evolution Parasite evolution Soil ecology Gut metagenome |
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Spatial dynamics of synthetic microbial mutualists and their parasitesAmor, Daniel R.Montañez, RaúlDuran Nebreda, Salvador, 1987-Solé Vicente, Ricard, 1962-Microbial ecologyMicrobial evolutionParasite evolutionSoil ecologyGut metagenomeA major force contributing to the emergence of novelty in nature is the presence of cooperative interactions, where two or more components of a system act in synergy, sometimes leading to higher-order, emergent phenomena. Within molecular evolution, the so called hypercycle defines the simplest model of an autocatalytic cycle, providing major theoretical insights on the evolution of cooperation in the early biosphere. These closed cooperative loops have also inspired our understanding of how catalytic loops appear in ecological systems. In both cases, hypercycle and ecological cooperative loops, the role played by space seems to be crucial for their stability and resilience against parasites. However, it is difficult to test these ideas in natural ecosystems, where time and spatial scales introduce considerable limitations. Here, we use engineered bacteria as a model system to a variety of environmental scenarios identifying trends that transcend the specific model system, such an enhanced genetic diversity in environments requiring mutualistic interactions. Interestingly, we show that improved environments can slow down mutualistic range expansions as a result of genetic drift effects preceding local resource depletion. Moreover, we show that a parasitic strain is excluded from the population during range expansions (which acknowledges a classical prediction). Nevertheless, environmental deterioration can reshape population interactions, this same strain becoming part of a three-species mutualistic web in scenarios in which the two-strain mutualism becomes non functional. The evolutionary and ecological implications for the design of synthetic ecosystems are outlined.This study was supported by an European Research Council Advanced Grant (SYNCOM, grant number 294294), a MINECO grant FIS2015-67616-P, by Banco Santander through its Santander Universities Global Division, the Secretaria d'Universitats i Recerca del Departament d'Economia i Coneixement de la Generalitat de Catalunya and by the Santa Fe Institute.Public Library of Science (PLoS)201820182017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/33733http://dx.doi.org/10.1371/journal.pcbi.1005689reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglésPLOS Computational Biology. 2017 Aug 21;13(8):e1005689info:eu-repo/grantAgreement/EC/FP7/294294info:eu-repo/grantAgreement/ES/1PE/FIS2015-67616-P© 2017 Amor et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/337332026-06-12T07:21:37Z |
| dc.title.none.fl_str_mv |
Spatial dynamics of synthetic microbial mutualists and their parasites |
| title |
Spatial dynamics of synthetic microbial mutualists and their parasites |
| spellingShingle |
Spatial dynamics of synthetic microbial mutualists and their parasites Amor, Daniel R. Microbial ecology Microbial evolution Parasite evolution Soil ecology Gut metagenome |
| title_short |
Spatial dynamics of synthetic microbial mutualists and their parasites |
| title_full |
Spatial dynamics of synthetic microbial mutualists and their parasites |
| title_fullStr |
Spatial dynamics of synthetic microbial mutualists and their parasites |
| title_full_unstemmed |
Spatial dynamics of synthetic microbial mutualists and their parasites |
| title_sort |
Spatial dynamics of synthetic microbial mutualists and their parasites |
| dc.creator.none.fl_str_mv |
Amor, Daniel R. Montañez, Raúl Duran Nebreda, Salvador, 1987- Solé Vicente, Ricard, 1962- |
| author |
Amor, Daniel R. |
| author_facet |
Amor, Daniel R. Montañez, Raúl Duran Nebreda, Salvador, 1987- Solé Vicente, Ricard, 1962- |
| author_role |
author |
| author2 |
Montañez, Raúl Duran Nebreda, Salvador, 1987- Solé Vicente, Ricard, 1962- |
| author2_role |
author author author |
| dc.subject.none.fl_str_mv |
Microbial ecology Microbial evolution Parasite evolution Soil ecology Gut metagenome |
| topic |
Microbial ecology Microbial evolution Parasite evolution Soil ecology Gut metagenome |
| description |
A major force contributing to the emergence of novelty in nature is the presence of cooperative interactions, where two or more components of a system act in synergy, sometimes leading to higher-order, emergent phenomena. Within molecular evolution, the so called hypercycle defines the simplest model of an autocatalytic cycle, providing major theoretical insights on the evolution of cooperation in the early biosphere. These closed cooperative loops have also inspired our understanding of how catalytic loops appear in ecological systems. In both cases, hypercycle and ecological cooperative loops, the role played by space seems to be crucial for their stability and resilience against parasites. However, it is difficult to test these ideas in natural ecosystems, where time and spatial scales introduce considerable limitations. Here, we use engineered bacteria as a model system to a variety of environmental scenarios identifying trends that transcend the specific model system, such an enhanced genetic diversity in environments requiring mutualistic interactions. Interestingly, we show that improved environments can slow down mutualistic range expansions as a result of genetic drift effects preceding local resource depletion. Moreover, we show that a parasitic strain is excluded from the population during range expansions (which acknowledges a classical prediction). Nevertheless, environmental deterioration can reshape population interactions, this same strain becoming part of a three-species mutualistic web in scenarios in which the two-strain mutualism becomes non functional. The evolutionary and ecological implications for the design of synthetic ecosystems are outlined. |
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2017 |
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2017 2018 2018 |
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info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
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article |
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publishedVersion |
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http://hdl.handle.net/10230/33733 http://dx.doi.org/10.1371/journal.pcbi.1005689 |
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http://hdl.handle.net/10230/33733 http://dx.doi.org/10.1371/journal.pcbi.1005689 |
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Inglés |
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Inglés |
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PLOS Computational Biology. 2017 Aug 21;13(8):e1005689 info:eu-repo/grantAgreement/EC/FP7/294294 info:eu-repo/grantAgreement/ES/1PE/FIS2015-67616-P |
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http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
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http://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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Public Library of Science (PLoS) |
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Public Library of Science (PLoS) |
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reponame:Repositorio Digital de la UPF instname:Universitat Pompeu Fabra |
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