Organocatalytic hydrophosphonylation reaction of carbonyl groups

This revision is covering the limited examples reported for a pivotal strategy in the formation of C-P bonds such as the asymmetric organocatalytic hydrophosphonylation of carbonyl groups (Pudovik reaction). The scope and limitations, and the proposed mechanisms for the scarce different possibilitie...

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Detalhes bibliográficos
Autor: Herrera, Raquel P.
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2017
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/184865
Acesso em linha:http://hdl.handle.net/10261/184865
Access Level:acceso abierto
Palavra-chave:Pudovik
Asymmetry
Hydrophosphonylation
Organocatalysis
Phosphite
α-hydroxy phosphonates
Descrição
Resumo:This revision is covering the limited examples reported for a pivotal strategy in the formation of C-P bonds such as the asymmetric organocatalytic hydrophosphonylation of carbonyl groups (Pudovik reaction). The scope and limitations, and the proposed mechanisms for the scarce different possibilities of asymmetric induction are also shown. The recent evolution and future trends of this undeveloped approach are commented.