A simple score to predict early severe infections in patients with newly diagnosed multiple myeloma

Infections remain a common complication in patients with multiple myeloma (MM) and are associated with morbidity and mortality. A risk score to predict the probability of early severe infection could help to identify the patients that would benefit from preventive measures. We undertook a post hoc a...

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Detalhes bibliográficos
Autores: Encinas, C.|||0000-0002-9001-9754, Hernández Rivas, José Ángel|||0000-0003-4550-757X, Oriol, Albert|||0000-0001-6804-2221, Rosiñol, Laura|||0000-0002-2534-9239, Blanchard, María Jesús, Bellón, José-María|||0000-0002-8492-1565, García-Sanz, Ramón|||0000-0003-4120-2787, de la Rubia, Javier|||0000-0002-8354-768X, López de la Guía, Ana, Jímenez-Ubieto, Ana, Jarque, Isidro|||0000-0001-5673-4490, Iñigo, Belén, Dourdil, Victoria, De Arriba, Felipe|||0000-0002-4451-1318, Cuéllar Pérez-Ávila, Clara, Gonzalez, Yolanda, Hernández, Miguel-Teodoro, Bargay, Joan|||0000-0002-6739-3916, Granell, Miquel|||0000-0002-0366-3673, Rodriguez-Otero, Paula|||0000-0001-5236-7785, Silvent, Maialen, Cabrera, Carmen, Ríos-Tamayo, Rafael|||0000-0001-8193-1402, Alegre, Adrian|||0000-0002-2423-822X, Gironella, Mercedes|||0000-0002-8106-8909, Gonzalez, Marta-Sonia, Sureda, Anna|||0000-0002-1238-6970, Sampol, Antonia|||0000-0001-7465-6203, Ocio, Enrique M.|||0000-0002-5765-0085, Krsnik, Isabel|||0000-0002-2912-5072, García, Antonio, García-Mateo, Aránzazu, Soler, Joan-Alfons, Martín Sánchez, Jesús|||0000-0003-4250-4824, Arguiñano, José M., Mateos, M. V.|||0000-0003-2390-1218, Bladé Creixenti, Juan|||0000-0002-4563-3405, San Miguel, Jesús|||0000-0002-9183-4857, Lahuerta, J. J.|||0000-0002-3393-9570, Martínez-López, Joaquín|||0000-0001-7908-0063
Formato: artículo
Fecha de publicación:2022
País:España
Recursos:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:280855
Acesso em linha:https://ddd.uab.cat/record/280855
https://dx.doi.org/urn:doi:10.1038/s41408-022-00652-2
Access Level:acceso abierto
Palavra-chave:Antibiotic Prophylaxis
Humans
Male
Multiple Myeloma
Descrição
Resumo:Infections remain a common complication in patients with multiple myeloma (MM) and are associated with morbidity and mortality. A risk score to predict the probability of early severe infection could help to identify the patients that would benefit from preventive measures. We undertook a post hoc analysis of infections in four clinical trials from the Spanish Myeloma Group, involving a total of 1347 patients (847 transplant candidates). Regarding the GEM2010.