A new synthetic approach to the lactol moiety of halichoblelide
A stereoselective approach to the γ-lactol moiety of halichoblelide is described starting from commercially available (R)-1-butyn-3-ol. The key step is the hydroboration of a chiral protected 1,2-butadien-3-ol and its addition to furfural.
| Autores: | , , , |
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| Formato: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2011 |
| País: | España |
| Recursos: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/117586 |
| Acesso em linha: | https://hdl.handle.net/2445/117586 |
| Access Level: | acceso abierto |
| Palavra-chave: | Síntesi orgànica Aldehids Organic synthesis Aldehydes |
| Resumo: | A stereoselective approach to the γ-lactol moiety of halichoblelide is described starting from commercially available (R)-1-butyn-3-ol. The key step is the hydroboration of a chiral protected 1,2-butadien-3-ol and its addition to furfural. |
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