Plasma-Assisted and Solvent-Free Ultra-Fast Synthesis of Gold and Gold Oxide Ultra-Small Nanoparticles and its use as Multi-Sensing Platforms.

In this work, a plasma-assisted and solvent-free synthesis of gold (Au) and gold oxide (Au(2)O(3)) nanoparticles (NPs) is explored. Accordingly, only the precursor (i.e., HAuCl(4) powder) is exposed to the N(2):O(2) plasma gas mixtures, selected to promote its reduction to Au (HAuCl(4)-to-Au(0)) and...

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Detalhes bibliográficos
Autores: Sans J, Colombi S, Arnau M, Fontana-Escartín A, Resina L, Garcia-Torres J, Alemán C
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Recursos:Fundació Sant Joan de Déu
Repositorio:r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
OAI Identifier:oai:fsjd.fundanetsuite.com:p29374
Acesso em linha:https://fsjd.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=29374
Access Level:acceso abierto
Palavra-chave:Au USNPs
Au2O3 NPs
multiplexing detection
plasma technologies
sensing biological environments
Descrição
Resumo:In this work, a plasma-assisted and solvent-free synthesis of gold (Au) and gold oxide (Au(2)O(3)) nanoparticles (NPs) is explored. Accordingly, only the precursor (i.e., HAuCl(4) powder) is exposed to the N(2):O(2) plasma gas mixtures, selected to promote its reduction to Au (HAuCl(4)-to-Au(0)) and/or favor its further oxidation to Au(2)O(3). As a result, the production of highly crystalline spherical Au ultra-small NPs (USNPs) of 2.7 ± 0.7 nm and Au(2)O(3) edged pyramidal-like NPs of 18 ± 5 nm is obtained in very short times (i.e., 10 s(-1) min), showing excellent stability without the need to add any ligands. To investigate the potential features of the synthesized particles, they are loaded into alginate hydrogels and tested as multi-detection sensor platforms of H(2)O(2) and NADH in front of several interferents. Although both samples present excellent electrochemical sensing activity (as compared to Au NPs synthesized through the Turkevich method), Au(2)O(3) NPs stand out for its high analytical sensibility toward H(2)O(2) (153.1 and 16.8 µA mm(-1) cm(-2) for single and multiplexing detection, simultaneously); and capacity to measure NADH in real human urine and low detection limits produced by Escherichia coli (7.5 × 10(3) CFU mL(-1)). Herein, a green, easy, and fast method is proposed to produce stable Au USNPs and Au(2)O(3) NPs, showing great potential for the catalytic and biomedical fields.