Evaluation of the potential therapeutic effects of a double-stranded RNA mimic complexed with polycations in an experimental mouse model of endometriosis.

To assess the therapeutic potential of polyinosine-polycytidylic acid, a double-stranded RNA molecule with selective proapoptotic and antiangiogenic activity, complexed with polyethyleneimine (pIC(PEI)) in treating endometriosis.

Detalles Bibliográficos
Autores: García-Pascual, Carmen Maria, Martínez, Jessica, Calvo, Paula, Ferrero, Hortensia, Villanueva, Ana, Pozuelo-Rubio, Mercedes, Soengas, MS, Tormo, Damiá, Simón, Carlos, Pellicer, Antonio, Gómez, Raúl
Tipo de recurso: artículo
Fecha de publicación:2015
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/25420
Acceso en línea:https://hdl.handle.net/20.500.12105/25420
Access Level:acceso abierto
Palabra clave:Endometriosis
angiogenesis
apoptosis
mouse model
pIC(PEI)
Descripción
Sumario:To assess the therapeutic potential of polyinosine-polycytidylic acid, a double-stranded RNA molecule with selective proapoptotic and antiangiogenic activity, complexed with polyethyleneimine (pIC(PEI)) in treating endometriosis.

Similares en LA Referencia