Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation Model

Estimating the cost of thalassemia care is important for the optimization of care planning, resource allocation and the empowerment of patient advocacy. However, available evidence is heterogeneous, reflecting diverse healthcare systems and cost estimation methods. We sought to build a globally appl...

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Autores: Eleftheriou, Androulla, Antoniou, Eleni, Darbà, Josep, Ascanio, Meritxell, Angastiniotis, Michael, Farmakis, Dimitrios
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2022
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/197757
Acceso en línea:https://hdl.handle.net/2445/197757
Access Level:acceso abierto
Palabra clave:Transfusió de sang
Talassèmia
Economia de la salut
Blood transfusion
Thalassemia
Medical economics
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spelling Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation ModelEleftheriou, AndroullaAntoniou, EleniDarbà, JosepAscanio, MeritxellAngastiniotis, MichaelFarmakis, DimitriosTransfusió de sangTalassèmiaEconomia de la salutBlood transfusionThalassemiaMedical economicsEstimating the cost of thalassemia care is important for the optimization of care planning, resource allocation and the empowerment of patient advocacy. However, available evidence is heterogeneous, reflecting diverse healthcare systems and cost estimation methods. We sought to build a globally applicable cost model for thalassemia care. We followed a three-step approach, including (i) a targeted literature review to identify previous cost-of-illness studies on thalassemia; (ii) a generic model development based on the main determinants of cost in different countries emerged from a literature review and validated by a team of medical experts; (iii) a piloting of the model using data from two diverse countries. The literature review revealed studies focusing on the total costs of thalassemia care or the cost or cost-effectiveness of specific treatment or prevention modalities in high- and low-prevalence countries across the world. The resulting evidence was used to build a model that calculates total annual therapy cost based on entry of country-level and patient-level data, and data on healthcare modalities, indirect costs and prevention. Testing the model using published data from the UK, Iran, India and Malaysia, revealed an annual cost per patient of £81,796.00 for the UK, Iranian rial (IRR) 13,757.00 for Iran, Indian rupee (INR) 166,750.00 for India and Malyasian ringgit (or dollar) (MYR) 111,372.00 for Malaysia. A globally applicable model that calculates total annual cost of thalassemia care was built based on existing evidence. The model successfully predicted the annual cost of thalassemia care in the UK, Iran, India and Malaysia.Marcel Dekker2023202420222023info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion4 p.application/pdfhttps://hdl.handle.net/2445/197757Articles publicats en revistes (Economia)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1080/03630269.2023.2167657Hemoglobin, 2022, vol. 46, num. 6, p. 308-311https://doi.org/10.1080/03630269.2023.2167657(c) Marcel Dekker, 2022info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1977572026-05-29T05:05:01Z
dc.title.none.fl_str_mv Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation Model
title Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation Model
spellingShingle Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation Model
Eleftheriou, Androulla
Transfusió de sang
Talassèmia
Economia de la salut
Blood transfusion
Thalassemia
Medical economics
title_short Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation Model
title_full Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation Model
title_fullStr Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation Model
title_full_unstemmed Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation Model
title_sort Estimating the Cost of Thalassemia Care across the World: A Thalassemia International Federation Model
dc.creator.none.fl_str_mv Eleftheriou, Androulla
Antoniou, Eleni
Darbà, Josep
Ascanio, Meritxell
Angastiniotis, Michael
Farmakis, Dimitrios
author Eleftheriou, Androulla
author_facet Eleftheriou, Androulla
Antoniou, Eleni
Darbà, Josep
Ascanio, Meritxell
Angastiniotis, Michael
Farmakis, Dimitrios
author_role author
author2 Antoniou, Eleni
Darbà, Josep
Ascanio, Meritxell
Angastiniotis, Michael
Farmakis, Dimitrios
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Transfusió de sang
Talassèmia
Economia de la salut
Blood transfusion
Thalassemia
Medical economics
topic Transfusió de sang
Talassèmia
Economia de la salut
Blood transfusion
Thalassemia
Medical economics
description Estimating the cost of thalassemia care is important for the optimization of care planning, resource allocation and the empowerment of patient advocacy. However, available evidence is heterogeneous, reflecting diverse healthcare systems and cost estimation methods. We sought to build a globally applicable cost model for thalassemia care. We followed a three-step approach, including (i) a targeted literature review to identify previous cost-of-illness studies on thalassemia; (ii) a generic model development based on the main determinants of cost in different countries emerged from a literature review and validated by a team of medical experts; (iii) a piloting of the model using data from two diverse countries. The literature review revealed studies focusing on the total costs of thalassemia care or the cost or cost-effectiveness of specific treatment or prevention modalities in high- and low-prevalence countries across the world. The resulting evidence was used to build a model that calculates total annual therapy cost based on entry of country-level and patient-level data, and data on healthcare modalities, indirect costs and prevention. Testing the model using published data from the UK, Iran, India and Malaysia, revealed an annual cost per patient of £81,796.00 for the UK, Iranian rial (IRR) 13,757.00 for Iran, Indian rupee (INR) 166,750.00 for India and Malyasian ringgit (or dollar) (MYR) 111,372.00 for Malaysia. A globally applicable model that calculates total annual cost of thalassemia care was built based on existing evidence. The model successfully predicted the annual cost of thalassemia care in the UK, Iran, India and Malaysia.
publishDate 2022
dc.date.none.fl_str_mv 2022
2023
2023
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/197757
url https://hdl.handle.net/2445/197757
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1080/03630269.2023.2167657
Hemoglobin, 2022, vol. 46, num. 6, p. 308-311
https://doi.org/10.1080/03630269.2023.2167657
dc.rights.none.fl_str_mv (c) Marcel Dekker, 2022
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Marcel Dekker, 2022
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 4 p.
application/pdf
dc.publisher.none.fl_str_mv Marcel Dekker
publisher.none.fl_str_mv Marcel Dekker
dc.source.none.fl_str_mv Articles publicats en revistes (Economia)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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