Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits

BACKGROUND: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological alterations could lead to difficulties in interpreting and managing life events resulting in a higher risk of s...

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Autores: Fernández Sevillano, Jessica, González Pinto Arrillaga, Ana María, Rodríguez-Revuelta, Julia, Alberich, Susana, González Blanco, Leticia, Zorrilla Martínez, Iñaki, Velasco, Ángela, López Peña, María Purificación, Abad, Iciar, Sáiz, Pilar Alejandra
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/50341
Acceso en línea:http://hdl.handle.net/10810/50341
Access Level:acceso abierto
Palabra clave:cognition
neuropsychological functioning
suicide
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spelling Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficitsFernández Sevillano, JessicaGonzález Pinto Arrillaga, Ana MaríaRodríguez-Revuelta, JuliaAlberich, SusanaGonzález Blanco, LeticiaZorrilla Martínez, IñakiVelasco, ÁngelaLópez Peña, María PurificaciónAbad, IciarSáiz, Pilar Alejandracognitionneuropsychological functioningsuicideBACKGROUND: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological alterations could lead to difficulties in interpreting and managing life events resulting in a higher risk of suicide. METHOD: A systematic literature search from 2000 to 2020 was performed in Medline (Pubmed), Web of Science, SciELO Citation Index, PsycInfo, PsycArticles and Cochrane Library databases regarding studies comparing cognition of attempters versus non-attempters that share same psychiatric diagnosis. RESULTS: 1.885 patients diagnosed with an Affective Disorder (n=1512) and Schizophrenia/ Schizoaffective Disorder (n=373) were included. In general comparison, attention was found to be clearly dysfunctional. Regarding diagnosis, patients with Schizophrenia and previous history of suicidal behaviour showed a poorer performance in executive function. Patients with current symptoms of an Affective Disorder and a previous history of suicidal attempt had poorer performance in attention and executive function. Similarly, euthymic affective patients with history of suicidal behaviour had worse decision-making, attention and executive function performance compared to euthymic non-attempters. LIMITATIONS: The number of papers included in this review is limited to the few studies using non-attempter clinically-matched control group and therefore results regarding diagnosis, symptomatology and time of the attempt are modest and contradictory. CONCLUSIONS: Patients who have attempted suicide have a poorer neuropsychological functioning than non-attempters with a similar psychiatric disorder in attention and executive function. These alterations increase vulnerability for suicide.This work was supported by Carlos III Health Research Institute[grant numbers PI14/02029, PI15/00793, PI15/00789, PI16/01164,PI17/01433 and PI18/01055 (co-financed by the European RegionalDevelopment Fund(FEDER/ERDF)/European Social Fund‘Investing inyour future’ and the Government of the Principality of Asturias PCTI-2018–2022 IDI/2018/235)], Foundation for Health Innovation andResearch (BIOEF); Bioaraba Research Institute; Networking Center forBiomedical Research in Mental Health (CIBERSAM), the BasqueGovernment [grant numbers 2015111024, 2017111104] and theUniversity of the Basque Country [grant number 321212ELBY]. Thepsychiatric research department in Araba University Hospital is sup-portedbytheStanleyResearchFoundation[grantnumber03-RC-003.Elsevier202120212021info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10810/50341reponame:Addi. Archivo Digital para la Docencia y la Investigacióninstname:Universidad del País VascoIngléshttps://www.sciencedirect.com/science/article/pii/S0165032720327397?via%3Dihub#!info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/3.0/es/2020 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).Atribución 3.0 EspañaAtribución-NoComercial-SinDerivadas 3.0 Españaoai:addi.ehu.eus:10810/503412026-06-18T09:23:17Z
dc.title.none.fl_str_mv Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
spellingShingle Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
Fernández Sevillano, Jessica
cognition
neuropsychological functioning
suicide
title_short Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title_full Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title_fullStr Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title_full_unstemmed Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
title_sort Suicidal behaviour and cognition: A systematic review with special focus on prefrontal deficits
dc.creator.none.fl_str_mv Fernández Sevillano, Jessica
González Pinto Arrillaga, Ana María
Rodríguez-Revuelta, Julia
Alberich, Susana
González Blanco, Leticia
Zorrilla Martínez, Iñaki
Velasco, Ángela
López Peña, María Purificación
Abad, Iciar
Sáiz, Pilar Alejandra
author Fernández Sevillano, Jessica
author_facet Fernández Sevillano, Jessica
González Pinto Arrillaga, Ana María
Rodríguez-Revuelta, Julia
Alberich, Susana
González Blanco, Leticia
Zorrilla Martínez, Iñaki
Velasco, Ángela
López Peña, María Purificación
Abad, Iciar
Sáiz, Pilar Alejandra
author_role author
author2 González Pinto Arrillaga, Ana María
Rodríguez-Revuelta, Julia
Alberich, Susana
González Blanco, Leticia
Zorrilla Martínez, Iñaki
Velasco, Ángela
López Peña, María Purificación
Abad, Iciar
Sáiz, Pilar Alejandra
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv cognition
neuropsychological functioning
suicide
topic cognition
neuropsychological functioning
suicide
description BACKGROUND: Suicide is a major health concern worldwide, thus, identifying risk factors would enable a more comprehensive understanding and prevention of this behaviour. Neuropsychological alterations could lead to difficulties in interpreting and managing life events resulting in a higher risk of suicide. METHOD: A systematic literature search from 2000 to 2020 was performed in Medline (Pubmed), Web of Science, SciELO Citation Index, PsycInfo, PsycArticles and Cochrane Library databases regarding studies comparing cognition of attempters versus non-attempters that share same psychiatric diagnosis. RESULTS: 1.885 patients diagnosed with an Affective Disorder (n=1512) and Schizophrenia/ Schizoaffective Disorder (n=373) were included. In general comparison, attention was found to be clearly dysfunctional. Regarding diagnosis, patients with Schizophrenia and previous history of suicidal behaviour showed a poorer performance in executive function. Patients with current symptoms of an Affective Disorder and a previous history of suicidal attempt had poorer performance in attention and executive function. Similarly, euthymic affective patients with history of suicidal behaviour had worse decision-making, attention and executive function performance compared to euthymic non-attempters. LIMITATIONS: The number of papers included in this review is limited to the few studies using non-attempter clinically-matched control group and therefore results regarding diagnosis, symptomatology and time of the attempt are modest and contradictory. CONCLUSIONS: Patients who have attempted suicide have a poorer neuropsychological functioning than non-attempters with a similar psychiatric disorder in attention and executive function. These alterations increase vulnerability for suicide.
publishDate 2021
dc.date.none.fl_str_mv 2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10810/50341
url http://hdl.handle.net/10810/50341
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://www.sciencedirect.com/science/article/pii/S0165032720327397?via%3Dihub#!
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
Atribución 3.0 España
Atribución-NoComercial-SinDerivadas 3.0 España
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/3.0/es/
Atribución 3.0 España
Atribución-NoComercial-SinDerivadas 3.0 España
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Addi. Archivo Digital para la Docencia y la Investigación
instname:Universidad del País Vasco
instname_str Universidad del País Vasco
reponame_str Addi. Archivo Digital para la Docencia y la Investigación
collection Addi. Archivo Digital para la Docencia y la Investigación
repository.name.fl_str_mv
repository.mail.fl_str_mv
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