Methicillin-resistant and methicillin-sensitive Staphylococcus aureus in pork industry workers, Catalonia, Spain

Methicillin-resistant S. aureus (MRSA) especially ST398, is a zoonotic agent. This study aimed to determine the prevalence of methicillin-susceptible S. aureus (MSSA) and MRSA among workers in the pork production chain. 659 workers associated with 123 pig farms, livestock transporters, one pig slaug...

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Detalles Bibliográficos
Autores: Quero, Sara|||0000-0002-6454-6358, Serras-Pujol, Marina, Párraga-Niño, Noemí|||0000-0003-0376-5036, Torres, Carmen, Navarro, Marian, Vilamala, Anna, Puigoriol, Emma, de los Ríos, Javier Diez, Arqué, Elisenda, Serra-Pladevall, Judit|||0000-0002-4798-2385, Romero, Alba, Molina, Daniel, Paredes, Roger|||0000-0002-6553-691X, Pedro Botet, Maria Luisa|||0000-0001-7252-3191, Reynaga, Esteban|||0000-0002-4069-6087
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:293147
Acceso en línea:https://ddd.uab.cat/record/293147
https://dx.doi.org/urn:doi:10.1016/j.onehlt.2023.100538
Access Level:acceso abierto
Palabra clave:Staphylococcus aureus
MRSA
LA-MRSA
MRSA-ST398
Spain
Pork industry workers
Descripción
Sumario:Methicillin-resistant S. aureus (MRSA) especially ST398, is a zoonotic agent. This study aimed to determine the prevalence of methicillin-susceptible S. aureus (MSSA) and MRSA among workers in the pork production chain. 659 workers associated with 123 pig farms, livestock transporters, one pig slaughterhouse, pork transporters and 23 pork butcheries were studied for S. aureus recovery, and all isolates were characterized (antibiotic resistance, MLST and spa -typing). The prevalence of S. aureus was 35.5%, 75.6% of isolates being MRSA. The prevalence of MRSA was 68.7% (149/217) among pig farm, 33.9% (19/56) livestock transporters, 2.9% (9/306) slaughterhouse, 0% in pork transporters (0/36) and butchery workers (0/44). Of the 234 S. aureus -positive workers, 100% (149/149) of pig farm workers, 82.6% (19/23) of livestock transporters, and 16.4% (9/55) of slaughterhouse workers carried MRSA isolates (p < 0.001). Of the workers who had contact with live swine, 61.8% (178/288) were S. aureus -positive, MRSA being detected in 96.1% of cases (p < 0.001). The most frequent lineage among MRSA were: ST398 (97.7%; 173/177) and ST1 (1.7%; 3/177); and among MSSA were ST30 (19.2%; 11/57) and ST5 (10.5%; 6/57). The most frequent spa -types among MRSA were t011 (93.8%, 166/177) and t1451 (2.25%, 4/177), and among MSSA: t084 (10.5%, 6/57) and t021 (7.0%, 4/57). All MRSA isolates showed resistance to tetracycline, 92.7% to clindamycin, 81.9% to erythromycin and 40.1% to cotrimoxazole. Pig industry workers having occupational contact with live animals present a high risk of colonization of MRSA, especially by MRSA-ST398. Prevention measures should be intensified in any employment sector involving live animals.