Dataset related to article: Simultaneous determination of six antipsychotics, two of their metabolites and caffeine in human plasma by LC-MS/MS using a phospholipid-removal microelution-solid phase extraction method for sample preparation

File 1. This xls files shows the data related to the main charateristics used for the development and validation of the new method as long as the measures for letting assure the repeatability and intermediate precision and accuracy values. The results obtained for the pharmacokinetic parameters are...

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Detalhes bibliográficos
Autores: Koller, Dora, Zubiaur, Pablo, Saiz-Rodríguez, Miriam, Abad-Santos, Francisco, Wojnicz, Aneta
Formato: conjunto de datos
Fecha de publicación:2021
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/245512
Acesso em linha:http://hdl.handle.net/10261/245512
Access Level:acceso abierto
Palavra-chave:Antipsychotics
Caffeine
Liquid chromatography-tandem mass spectrometry
Phospholipids
Solid phase extraction
Therapeutic drug monitoring
Descrição
Resumo:File 1. This xls files shows the data related to the main charateristics used for the development and validation of the new method as long as the measures for letting assure the repeatability and intermediate precision and accuracy values. The results obtained for the pharmacokinetic parameters are also included in the file File 2 This jpg file shows the product ion spectra and chemical structures of the antipsychotics and their metabolites obtained by collision-induced dissociation (CID) of the indicated precursor ions [M+H]+. The fragmentation patterns of all analytes are indicated by an arrow on their chemical structure of each analyte. The results are presented as the percentage of counts versus Mass-to-Charge (m/z). All mass peaks have been normalized to the most abundant