Development of PVA/gelatin nanofibrous scaffolds for Tissue Engineering via electrospinning

The electrospinning process is an emerging and relatively easy technique to prepare three-dimensional matrices with micro- and nanofibers. To achieve it, aqueous polymer solutions from synthetic or natural polymers are used. PVA was selected as polymer and gelatin because of its biocompatibility and...

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Detalles Bibliográficos
Autores: Pérez-Puyana, Víctor Manuel, Jiménez-Rosado, Mercedes, Romero García, Alberto, Guerrero Conejo, Antonio Francisco
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/107449
Acceso en línea:https://hdl.handle.net/11441/107449
https://doi.org/10.1088/2053-1591/aab164
Access Level:acceso abierto
Palabra clave:Gelatin
Viscosity
Electrospinning
Scaffolds
Nanofibers
Descripción
Sumario:The electrospinning process is an emerging and relatively easy technique to prepare three-dimensional matrices with micro- and nanofibers. To achieve it, aqueous polymer solutions from synthetic or natural polymers are used. PVA was selected as polymer and gelatin because of its biocompatibility and biodegradability. A complete characterization of the polymeric solutions (density, surface tension, etc) was previously performed. Subsequently, a standard electrospinning process (15 kV, 0.4 ml h−1 and 10 cm) was carried out to obtain scaffolds. The influence of the polymer concentration and the protein addition was observed by performing FTIR analyses and studied by analyzing the water contact angle and SEM images.